ReviewScience translational medicine2018
Cancer metabolism gets physical.
Review in Science translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Bioengineered systems to exploit tumor microenvironment metabolism.Trends in cancer · 2026Review
- Crosstalk between metabolism and cell death in tumorigenesis.Molecular cancer · 2024Review
- A two-way street - cellular metabolism and myofibroblast contraction.NPJ Regenerative medicine · 2024Review
- The role and mechanism of compressive stress in tumor.Frontiers in oncology · 2024Review
- Screening in serum-derived medium reveals differential response to compounds targeting metabolism.Cell chemical biology · 2023Article
- Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer.Cell reports. Medicine · 2023Article
- Screening in serum-derived medium reveals differential response to compounds targeting metabolism.bioRxiv : the preprint server for biology · 2023Article
- Mechanical and metabolic interplay in the brain metastatic microenvironment.Frontiers in oncology · 2022Article
- Pinpointing Cancer Sub-Type Specific Metabolic Tasks Facilitates Identification of Anti-cancer Targets.Frontiers in medicine · 2022Article
- Article
- Engineering strategies to capture the biological and biophysical tumor microenvironment in vitro.Advanced drug delivery reviews · 2021Review
- Mechanoresponsive metabolism in cancer cell migration and metastasis.Cell metabolism · 2021Review
- Adhesion-mediated mechanosignaling forces mitohormesis.Cell metabolism · 2021Article
- Osmotic pressure modulates single cell cycle dynamics inducing reversible growth arrest and reactivation of human metastatic cells.Scientific reports · 2021Article
- Integration of mechanical and ECM microenvironment signals in the determination of cancer stem cell states.Current stem cell reports · 2021Article
- Immunometabolic Interplay in the Tumor Microenvironment.Cancer cell · 2021Review
- Crosstalk between mechanotransduction and metabolism.Nature reviews. Molecular cell biology · 2021Review
- Physical traits of cancer.Science (New York, N.Y.) · 2020Review
- Polyphenolic Proanthocyanidin-B2 suppresses proliferation of liver cancer cells and hepatocellular carcinogenesis through directly binding and inhibiting AKT activity.Redox biology · 2020Article
- Obesity, sleep apnea, and cancer.International journal of obesity (2005) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Patient-derived culture models enable assessment of drug sensitivity and can connect personalized genomics with therapeutic options. However, their clinical translation is constrained by limited fidelity. We outline how the physical microenvironment regulates cell metabolism and describe how engineered culture systems could enhance the predictive power for precision medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.