ArticleProceedings. Biological sciences2018
Mitochondrial genetic effects on reproductive success: signatures of positive intrasexual, but negative intersexual pleiotropy.
Article in Proceedings. Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Mito-nuclear incompatibility disrupts acyl-CoA oxidase 1/acyl-CoA oxidase 3-mediated mitochondria-peroxisome metabolic coordination in black soldier flies.Molecular biology and evolution · 2026Article
- The role of mitotype variation and positive epistasis in trait differences between Saccharomyces species.Genetics · 2026Article
- Testing the Mother's Curse Hypothesis in Human Mitochondrial Genome Evolution.Genome biology and evolution · 2025Article
- Article
- A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila.PLoS genetics · 2024Article
- Mother's Curse effects on lifespan and aging.Frontiers in aging · 2024Review
- Review
- Mitochondrial effects on fertility and longevity inProceedings. Biological sciences · 2022Article
- Effects of mitochondrial haplotype on pre-copulatory mating success in male fruit flies (Drosophila melanogaster).Journal of evolutionary biology · 2022Article
- The Reserve/Maximum Capacity of Melatonin's Synthetic Function for the Potential Dimorphism of Melatonin Production and Its Biological Significance in Mammals.Molecules (Basel, Switzerland) · 2021Review
- Mitonuclear Interactions Produce Diverging Responses to Mild Stress inFrontiers in genetics · 2021Article
- Sibling rivalry versus mother's curse: can kin competition facilitate a response to selection on male mitochondria?Proceedings. Biological sciences · 2020Article
- Nutritional geometry of mitochondrial genetic effects on male fertility.Biology letters · 2020Article
- Sex-specific effects of mitochondrial haplotype on metabolic rate inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Sperm competitive advantage of a rare mitochondrial haplogroup linked to differential expression of mitochondrial oxidative phosphorylation genes.Journal of evolutionary biology · 2019Article
- Temperature-Sensitive Reproduction and the Physiological and Evolutionary Potential for Mother's Curse.Integrative and comparative biology · 2019Article
- Selfish Mitonuclear Conflict.Current biology : CB · 2019Review
- Age of Both Parents Influences Reproduction and Egg Dumping Behavior in Drosophila melanogaster.The Journal of heredity · 2019Article
- The cuticle inward barrier inPeerJ · 2019Article
- Maternal age effects on fecundity and offspring egg-to-adult viability are not affected by mitochondrial haplotype.Ecology and evolution · 2018Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Theory predicts that maternal inheritance of mitochondria will facilitate the accumulation of mtDNA mutations that are male biased, or even sexually antagonistic, in effect. While there are many reported cases of mtDNA mutations conferring cytoplasmic male sterility in plants, historically it was assumed such mutations would not persist in the streamlined mitochondrial genomes of bilaterian metazoans. Intriguingly, recent cases of mitochondrial variants exerting male biases in effect have come to light in bilaterians. These cases aside, it remains unknown whether the mitochondrial genetic variation affecting phenotypic expression, and in particular reproductive performance, in bilaterians is routinely composed of sex-biased or sex-specific variation. If selection consistently favours mtDNA variants that augment female fitness, but at cost to males, this could shape patterns of pleiotropy and lead to negative intersexual correlations across mtDNA haplotypes. Here, we show that genetic variation across naturally occurring mitochondrial haplotypes affects components of reproductive success in both sexes, in the fruit fly
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