Evidence map›Paper›PMID 29793982›Full record

ArticlePeritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

Peritoneal Dialysis for AKI in Cameroon: Commercial vs Locally-Made Solutions.

Dennis Palmer, William J Lawton, Charles Barrier, B D Fine, Hayden Hemphill, Norah Ndi Nyah, Virginie Kinne, Njaprim Ivor Ringnwi, Genevive Yong, Amy L Neufeldt and 3 more

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Article in Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

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  12. Local solutions save young lives.Nature reviews. Nephrology · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Dennis PalmerMbingo Baptist Hospital, Mbingo, Cameroon.
William J LawtonRoy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.
Charles BarrierUNC School of Medicine, Chapel Hill, NC, USA.
B D FineArkansas Renal Group, Hot Springs, AR, USA.
Hayden HemphillCollom and Carney Clinic, Texarkana, TX, USA.
Norah Ndi NyahMbingo Baptist Hospital, Mbingo, Cameroon.
Virginie KinneMbingo Baptist Hospital, Mbingo, Cameroon.
Njaprim Ivor RingnwiMbingo Baptist Hospital, Mbingo, Cameroon.
Genevive YongMbingo Baptist Hospital, Mbingo, Cameroon.
Amy L NeufeldtStollery Children's Hospital, Edmonton, AB, Canada.
Yves MitterandMbingo Baptist Hospital, Mbingo, Cameroon.
Fredric O FinkelsteinYale University, New Haven, CT, USA.
Thomas A KrahnWarren Alpert Medical School of Brown University, Providence, RI, USA Thomas_Krahn@brown.edu.
Cameroon Baptist Convention Health Services · CMBrown University · USStollery Children's Hospital · CAUniversity of Massachusetts Chan Medical School · USUniversity of North Carolina Health Care · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is common in low- and middle-income countries, and is associated with a high mortality. The high mortality rate is in large part due to the inability to perform dialysis in resource-limited settings. Due to significant cost advantages, peritoneal dialysis (PD) has been used to treat AKI in these settings. The costs, however, remain high when commercial solutions are used.

methodsThis is a retrospective cohort study of the outcome, and of the peritonitis rates, of patients with AKI treated with either commercially manufactured PD solutions or locally-made PD solutions. A program to treat AKI with PD was started at Mbingo Baptist Hospital in Cameroon. Between May 2013 and January 2015, solutions and connection sets were provided by the Saving Young Lives Program. From January 2015 through March 2017, solutions were locally produced and available tubing was used.

resultsMortality in hospitalized AKI patients was 28% during the period when commercial solutions and tubing were utilized, and 33% when locally produced solutions and available tubing were utilized. In both groups, peritonitis occurred in 16% of treatment courses.

conclusionsLocally produced PD solutions, used with locally available tubing, were used to treat AKI with PD. The mortality and peritonitis rates were similar whether locally produced or commercial supplies were used.

Indexed as

Developing CountriesDrug CompoundingPeritoneal DialysisAcute Kidney InjuryAdolescentAdultAgedCameroonChildChild, PreschoolDialysis SolutionsFemaleHumansInfantMaleMiddle AgedDialysis Solutionseconomics of dialysisLow- and middle-income countriesmortality of acute kidney injuryperitonitis

Identifiers

PMID29793982
OpenAlexW2804696336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.