ArticleThe Journal of general physiology2018
Tetrodotoxin-sensitive Na
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Article in The Journal of general physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Selective activation of tetrodotoxin-sensitive sodium channels by AaH-II drives arrhythmogenic late Na+ current in the heart.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Restoration of mitochondrial CaJournal of molecular and cellular cardiology · 2026Article
- Selectivity Filter Mutation in NaJACC. Clinical electrophysiology · 2026Article
- Sodium Channel Isoform Diversity Underlies Chamber-Specific Cardiac Excitability.Circulation research · 2026Article
- SARS-CoV-2 spike protein-induced inflammation underlies proarrhythmia in COVID-19.Scientific reports · 2025Article
- Article
- Riluzole is associated with reduced risk of heart failure.European journal of neurology · 2025Article
- A Possible Role of Tetrodotoxin-Sensitive NaInternational journal of molecular sciences · 2024Article
- Cardiac-Specific Deletion of Scn8a Mitigates Dravet Syndrome-Associated Sudden Death in Adults.JACC. Clinical electrophysiology · 2024Article
- Vascular Endothelial Barrier Protection Prevents Atrial Fibrillation by Preserving Cardiac Nanostructure.JACC. Clinical electrophysiology · 2023Article
- NaV1.6 dysregulation within myocardial T-tubules by D96V calmodulin enhances proarrhythmic sodium and calcium mishandling.The Journal of clinical investigation · 2023Article
- MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia.International journal of molecular sciences · 2022Article
- Drug-Related Lymphedema: Mysteries, Mechanisms, and Potential Therapies.Frontiers in pharmacology · 2022Review
- NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis.Cardiovascular research · 2021Article
- Inhibition of cardiac potassium currents by oxidation-activated protein kinase A contributes to early afterdepolarizations in the heart.American journal of physiology. Heart and circulatory physiology · 2020Article
- Vascular endothelial growth factor promotes atrial arrhythmias by inducing acute intercalated disk remodeling.Scientific reports · 2020Article
- Tetrodotoxin-Sensitive Neuronal-Type NaJournal of the American Heart Association · 2020Article
- Super-Resolution Imaging Using a Novel High-Fidelity Antibody Reveals Close Association of the Neuronal Sodium Channel NaMicroscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada · 2020Article
- Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules.Frontiers in physiology · 2019Article
- A privileged role for neuronal NaThe Journal of general physiology · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Megan KoleskeDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.ORCID 0000-0002-9826-6442
Ingrid BonillaDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.
Justin ThomasDivision of Pharmacy Practice and Sciences, College of Pharmacy, The Ohio State University, Columbus, OH.ORCID 0000-0002-6496-6387
Naveed ZamanDivision of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH.
Stephen BaineDivision of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH.ORCID 0000-0002-1671-4652
Bjorn C KnollmannDivision of Clinical Pharmacology, Vanderbilt University Medical School, Nashville, TN.
Rengasayee VeeraraghavanDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.ORCID 0000-0002-8364-2222
Sándor GyörkeDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.
Przemysław B RadwańskiDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH przemyslaw.radwanski@osumc.edu.ORCID 0000-0002-0750-2308
The Ohio State University Wexner Medical Center · USThe Ohio State University · USVanderbilt University Medical Center · US
Funding
CONTROLLED AND UNCONTROLLABLE CALCIUM RELEASE IN HEARTR01HL063043 · NHLBI · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI Sandor Gyorke · 1999 to 2026
$8.6MRyanodine Receptor Channels in Heart FailureR01HL074045 · NHLBI · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI GYORKE, SANDOR · 2003 to 2024
$8.2MRegulation and Dysregulation of Cardiac EC coupling by CalmodulinR01HL138579 · NHLBI · OHIO STATE UNIVERSITY · PI Jonathan Paul Davis, Sandor Gyorke · 2017 to 2026
$6.1MToward a Mechanism-Based Approach to Treating Atrial FibrillationR01HL124935 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KNOLLMANN, BJORN C · 2015 to 2019
$2.8MMicrodomain regulation of Ca2+ release in cardiac physiology and diseaseR00HL127299 · NHLBI · OHIO STATE UNIVERSITY · PI RADWANSKI, PRZEMYSLAW · 2017 to 2019
$740kNHLBI NIH HHS R00 HL127299NHLBI NIH HHS R01 HL063043NHLBI NIH HHS R01 HL074045NHLBI NIH HHS R01 HL124935NHLBI NIH HHS R01 HL138579
Abstract
Recent evidence suggests that neuronal Na
Indexed as
Membrane PotentialsAnimalsCalciumCalcium Channel BlockersCalcium Channels, L-TypeCalsequestrinCells, CulturedLong QT SyndromeMiceMice, Inbred C57BLMyocytes, CardiacSodium Channel BlockersSodium ChannelsTetrodotoxinCalciumCalcium Channel BlockersCalcium Channels, L-TypeCalsequestrinSodium Channel BlockersSodium ChannelsTetrodotoxin
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LicenceCC BY-NC-SA
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.