Evidence map›Paper›PMID 29793450›Full record

ArticleBMC cancer2018

Endogenous H

Jan Breza, Andrea Soltysova, Sona Hudecova, Adela Penesova, Ivan Szadvari, Petr Babula, Barbora Chovancova, Lubomira Lencesova, Ondrej Pos, Jan Breza and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Hydrogen Sulfide Biology and Its Role in Cancer.Molecules (Basel, Switzerland) · 2022
    Review
  13. Molecular Functions of Hydrogen Sulfide in Cancer.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021
    Review
  14. The Hidden Role of Hydrogen Sulfide Metabolism in Cancer.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Hydrogen Sulfide and the Kidney.Advances in experimental medicine and biology · 2021
    Article
  17. Mistimed HBiomedical reports · 2020
    Article
  18. Review
  19. Article
  20. Cells · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Jan BrezaDepartment of Urology with Kidney Transplant Center, University Hospital, Faculty of Medicine, Bratislava, Slovakia.
Andrea SoltysovaInstitute of Clinical and Translational Research, Biomedical Research Center, SAS, Bratislava, Slovakia.
Sona HudecovaInstitute of Clinical and Translational Research, Biomedical Research Center, SAS, Bratislava, Slovakia.
Adela PenesovaInstitute of Clinical and Translational Research, Biomedical Research Center, SAS, Bratislava, Slovakia.
Ivan SzadvariDepartment of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Petr BabulaDepartment of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Barbora ChovancovaInstitute of Clinical and Translational Research, Biomedical Research Center, SAS, Bratislava, Slovakia.
Lubomira LencesovaInstitute of Clinical and Translational Research, Biomedical Research Center, SAS, Bratislava, Slovakia.
Ondrej PosDepartment of Molecular Biology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Jan BrezaDepartment of Urology with Kidney Transplant Center, University Hospital, Faculty of Medicine, Bratislava, Slovakia.
Karol OndriasInstitute of Clinical and Translational Research, Biomedical Research Center, SAS, Bratislava, Slovakia.
Olga KrizanovaInstitute of Clinical and Translational Research, Biomedical Research Center, SAS, Bratislava, Slovakia. olga.krizanova@savba.sk.
Biomedical Research Center of the Slovak Academy of Sciences · SKMasaryk University · CZComenius University Bratislava · SKUniversity Hospital Bratislava · SK

Funding

Agentúra na Podporu Výskumu a Vývoja APVV- 14-0351Slovenská Akadémia Vied VEGA 2/0082/16
6 · The paper itself

Abstract

backgroundKnowledge about the expression and thus a role of enzymes that produce endogenous H

methodsTo determine the physiological importance, we used RCC4 stable cell line derived from clear cell renal cell carcinoma, where apoptosis induction by a mixture of five chemotherapeutics with/without silencing of H

resultsIn clear cell renal cell carcinomas, expression of H

conclusionBased on these results we concluded that in clear cell renal cell carcinoma, reduced expression of the H

Indexed as

ApoptosisAdultAgedCarcinoma, Renal CellCell Line, TumorCystathionine beta-SynthaseCystathionine gamma-LyaseFemaleHumansHydrogen SulfideKidneyKidney NeoplasmsMaleMiddle AgedNephrectomyRNA InterferenceCystathionine beta-SynthaseCystathionine gamma-LyaseHydrogen SulfideRNA, Small Interfering3-Mercaptopyruvate sulfurtransferaseApoptosisClear cell renal cell carcinomaCystathionine-β-synthaseCystathionine γ-lyase

Identifiers

PMID29793450
PMCPMC5968466
OpenAlexW2805387522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.