Evidence map›Paper›PMID 29793059›Full record

ArticleInternational journal for parasitology. Drugs and drug resistance2018

Longitudinal surveillance of drug resistance in Plasmodium falciparum isolates from the China-Myanmar border reveals persistent circulation of multidrug resistant parasites.

Yao Bai, Jiaqi Zhang, Jinting Geng, Shiling Xu, Shuang Deng, Weilin Zeng, Zenglei Wang, Huguette Gaelle Ngassa Mbenda, Jie Zhang, Na Li and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal for parasitology. Drugs and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Antimicrobial agents and chemotherapy · 2023
    Article
  9. Article
  10. A review of malaria molecular markers for drug resistance inFrontiers in cellular and infection microbiology · 2023
    Review
  11. Different In Vitro Drug Susceptibility Profile ofTropical medicine and infectious disease · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Frontiers in pharmacology · 2021
    Review
  16. Molecular Surveillance and in vitro Drug Sensitivity Study ofThe American journal of tropical medicine and hygiene · 2020
    Article
  17. Unsymmetrical Bisquinolines with High Potency againstMolecules (Basel, Switzerland) · 2020
    Article
  18. Genomic Epidemiology of Antimalarial Drug Resistance inFrontiers in cellular and infection microbiology · 2020
    Article
  19. Article
  20. Analysis of Plasmodium falciparum NaBMC infectious diseases · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Yao BaiDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China; Department of Pharmacology, Kunming Medical University, Kunming, China.
Jiaqi ZhangDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Jinting GengDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Shiling XuDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Shuang DengDepartment of Pathology, Kunming Medical University, Kunming, China.
Weilin ZengDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Zenglei WangDepartment of Entomology, The Pennsylvania State University, University Park, PA 16802, USA.
Huguette Gaelle Ngassa MbendaDepartment of Entomology, The Pennsylvania State University, University Park, PA 16802, USA.
Jie ZhangDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Na LiDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China; Department of Pharmacology, Kunming Medical University, Kunming, China.
Yanrui WuDepartment of Cell Biology and Medical Genetics, Kunming Medical University, Kunming, Yunnan Province 650500, China.
Cuiying LiDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Huae LiuDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Yonghua RuanDepartment of Pathology, Kunming Medical University, Kunming, China.
Yaming CaoDepartment of Immunology, China Medical University, Shenyang, Liaoning 110122 China.
Zhaoqing YangDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China. Electronic address: zhaoqingy92@hotmail.com.
Liwang CuiDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China; Department of Entomology, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address: luc2@psu.edu.
Kunming Medical University · CNPennsylvania State University · USChina Medical University · CN

Funding

Southeast Asia Malaria Research CenterU19AI089672 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2010 to 2023
$28.9M
Molecular Mechanisms of Artemisinin ResistanceR01AI128940 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2017 to 2021
$971k
NIAID NIH HHS R01 AI128940NIAID NIH HHS U19 AI089672
6 · The paper itself

Abstract

Multidrug-resistant Plasmodium falciparum in the Greater Mekong Subregion of Southeast Asia is a major threat to malaria elimination and requires close surveillance. In this study, we collected 107 longitudinal clinical samples of P. falciparum in 2007-2012 from the malaria hypoendemic region of the China-Myanmar border and measured their in vitro susceptibilities to 10 antimalarial drugs. Overall, parasites had significantly different IC

Indexed as

Drug Resistance, MultipleAntimalarialsArtemisininsATP-Binding Cassette, Sub-Family C ProteinsChinaChloroquineEpidemiological MonitoringGenotypeHumansInhibitory Concentration 50In Vitro TechniquesLumefantrineMalaria, FalciparumMutationMyanmarPlasmodium falciparumAntimalarialsArtemisininsartenimolATP-Binding Cassette, Sub-Family C ProteinsChloroquineLumefantrineProtozoan ProteinsChina-Myanmar borderDrug resistanceIn vitro assayMutationPlasmodium falciparum

Identifiers

PMID29793059
PMCPMC6039318
OpenAlexW2803379428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.