Evidence map›Paper›PMID 29792867›Full record

ArticleBrain research2018

Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood.

Luke K Sherrill, Joshua M Gulley

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Peri-adolescent exposure to (meth)amphetamine in animal models.International review of neurobiology · 2022
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Luke K SherrillDepartment of Psychology, University of Illinois, Urbana-Champaign, United States.
Joshua M GulleyDepartment of Psychology, University of Illinois, Urbana-Champaign, United States; Neuroscience Program, University of Illinois, Urbana-Champaign, United States; Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana-Champaign, United States. Electronic address: jgulley@illinois.edu.
University of Illinois Urbana-Champaign · US

Funding

Mechanisms of amphetamine-induced plasticity in adolescents compared to adultsR01DA029815 · NIDA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GULLEY, JOSHUA M · 2011 to 2015
$1.5M
NIDA NIH HHS R01 DA029815
6 · The paper itself

Abstract

Repeated exposure to psychostimulants during adolescence produces long-lasting changes in behavior that may be mediated by disrupted development of the mesocorticolimbic dopamine system. Here, we tested this hypothesis by assessing the effects of amphetamine (AMPH) and dopamine receptor-selective drugs on behavior and neuron activity in the prelimbic region of the medial prefrontal cortex (PFC). Adolescent male, Sprague-Dawley rats were given saline or 3 mg/kg AMPH between postnatal day (P) 27 and P45. In Experiment 1, locomotor behavior was assessed during adulthood following challenges with a dopamine D

Indexed as

AgingAmphetamineAnimalsBehavior, AnimalCentral Nervous System StimulantsDopamine AgonistsDopamine AntagonistsMaleMotor ActivityNeuronsPrefrontal CortexRatsReceptors, Dopamine D1Receptors, Dopamine D2Stereotyped BehaviorAmphetamineCentral Nervous System StimulantsDopamine AgonistsDopamine AntagonistsReceptors, Dopamine D1Receptors, Dopamine D2AdolescentD(1)receptorD(2)receptorDevelopmentLocomotor activitySensitization

Identifiers

PMID29792867
PMCPMC6026035
OpenAlexW2803831545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.