Evidence map›Paper›PMID 29792546›Full record

ArticleHuman vaccines & immunotherapeutics2018

Application of a mixture model to assess the effect of measles-mumps-rubella vaccine on the mumps epidemic in children from kindergarten to early school age in Jiangsu Province, China.

Lei Zhang, Zhiguo Wang, Ying Hu, Xiuying Deng, Hongxiong Guo, Xiang Sun, Fenyang Tang, Minghao Zhou, Yuanbao Liu

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lei Zhanga Department of Epidemiology , School of Public Health, Nanjing Medical University , Nanjing , Jiangsu province , China.ORCID http://orcid.org/0000-0002-0083-6583
Zhiguo Wangb Department of Expanded Program on Immunization , Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , Jiangsu province , China.
Ying Hub Department of Expanded Program on Immunization , Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , Jiangsu province , China.
Xiuying Dengb Department of Expanded Program on Immunization , Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , Jiangsu province , China.
Hongxiong Guob Department of Expanded Program on Immunization , Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , Jiangsu province , China.
Xiang Sunb Department of Expanded Program on Immunization , Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , Jiangsu province , China.
Fenyang Tangb Department of Expanded Program on Immunization , Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , Jiangsu province , China.
Minghao Zhoua Department of Epidemiology , School of Public Health, Nanjing Medical University , Nanjing , Jiangsu province , China.ORCID http://orcid.org/0000-0003-1504-3591
Yuanbao Liub Department of Expanded Program on Immunization , Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , Jiangsu province , China.
Jiangsu Provincial Center for Disease Control and Prevention · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A single dose of the measles-mumps-rubella (MMR) vaccine has been applied in routine immunizations for children in China; however, the Immunoglobulin G (IgG) antibody level of mumps in children from kindergarten to early school age with MMR vaccine immunization history has not been elucidated. This study aimed to describe the immunity profile of children from kindergarten to early school age to identify the susceptible population. In Jiangsu Province, a cross-sectional survey of 4- to 8-year-old children who were vaccinated with at least one dose of MMR vaccine was conducted. IgG antibody results were analyzed by employing both the Enzyme-Linked Immunosorbent Assay (ELISA) cutoff values and the mixture model. A total of 7436 eligible subjects were enrolled: 3386 subjects were in kindergarten, and 4450 were in primary school. The overall seroprevalence (75.4%, 95% CI: 74.4%-76.4%) and Geometric mean concentration (GMC, 201.4U/ml, 95% CI: 194.1-209.4) of mumps antibodies in 2016 were low. The seroprevalence of children in kindergarten (78.1%, 95% CI: 76.6%-79.4%) was significantly higher than that of children in primary school (73.2%, 95% CI: 71.2%-74.6%). The GMC was negatively correlated with the time of inoculation (F = 32.17,

Indexed as

geometric mean concentrationmixture modelmumpsseroprevalence

Identifiers

PMID29792546
PMCPMC6314428
OpenAlexW2804344362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.