Evidence map›Paper›PMID 29792241›Full record

Trial reportPsychological medicine2019

Efficacy of digital CBT for insomnia to reduce depression across demographic groups: a randomized trial.

Philip Cheng, Annemarie I Luik, Cynthia Fellman-Couture, Edward Peterson, Christine L M Joseph, Gabriel Tallent, Kieulinh Michelle Tran, Brian K Ahmedani, Timothy Roehrs, Thomas Roth and 1 more

2 registry-linked trialsAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Psychological medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 83 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04986007 naterminatednot on this mapstarted 2021, after this paper: background citation

Addressing Nocturnal Sleep/Wake Effects on Risk of Suicide in Older Adults (ANSWERS-OA): A Pilot, Open-Label, Randomized Controlled Trial of Digital Cognitive Behavioral Therapy for Insomnia

TypeinterventionalSponsorMICHAEL A GRANDNERRan2021 to 2025Enrolled23ConditionsSleep Initiation and Maintenance Disorders, Suicidal IdeationArmsDigital Cognitive Behavioral Therapy for Insomnia
NCT05568381 nacompletednot on this mapstarted 2023, after this paper: background citation

Sleep Disturbance in MCI: A Pilot Study of a Cognitive Behavioural Therapy Digital Intervention (SUCCEED)

TypeinterventionalSponsorUniversity of SydneyRan2023 to 2023Enrolled40ConditionsCognitive Dysfunction, Insomnia, Mild Cognitive Impairment, Cognitive DisorderArmsdigital CBT-I, Online Sleep Health Education package
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Philip ChengSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Annemarie I LuikDepartment of Clinical Neurosciences,University of Oxford,Oxford,UK.
Cynthia Fellman-CoutureSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Edward PetersonSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Christine L M JosephSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Gabriel TallentSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Kieulinh Michelle TranSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Brian K AhmedaniSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Timothy RoehrsSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Thomas RothSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.
Christopher L DrakeSleep Disorders and Research Center, Henry Ford Health System,Detroit, MI,USA.

Funding

Sleep to Reduce Incident Depression Effectively (STRIDE)R01MH122636 · NIMH · HENRY FORD HEALTH SYSTEM · PI DRAKE, CHRISTOPHER L · 2020 to 2022
$1.8M
Sleep to Reduce Incident Depression Effectively (STRIDE)R56MH115150 · NIMH · HENRY FORD HEALTH SYSTEM · PI DRAKE, CHRISTOPHER L · 2018 to 2019
$833k
Clinical translation of phenotypes of shift work disorderK23HL138166 · NHLBI · HENRY FORD HEALTH SYSTEM · PI CHENG, PHILIP · 2017 to 2021
$761k
NHLBI NIH HHS K23 HL138166NIMH NIH HHS R01 MH122636NIMH NIH HHS R56 MH115150
6 · The paper itself

Abstract

backgroundInsomnia and depression are highly comorbid and mutually exacerbate clinical trajectories and outcomes. Cognitive behavioral therapy for insomnia (CBT-I) effectively reduces both insomnia and depression severity, and can be delivered digitally. This could substantially increase the accessibility to CBT-I, which could reduce the health disparities related to insomnia; however, the efficacy of digital CBT-I (dCBT-I) across a range of demographic groups has not yet been adequately examined. This randomized placebo-controlled trial examined the efficacy of dCBT-I in reducing both insomnia and depression across a wide range of demographic groups.

methodsOf 1358 individuals with insomnia randomized, a final sample of 358 were retained in the dCBT-I condition and 300 in the online sleep education condition. Severity of insomnia and depression was examined as a dependent variable. Race, socioeconomic status (SES; household income and education), gender, and age were also tested as independent moderators of treatment effects.

resultsThe dCBT-I condition yielded greater reductions in both insomnia and depression severity than sleep education, with significantly higher rates of remission following treatment. Demographic variables (i.e. income, race, sex, age, education) were not significant moderators of the treatment effects, suggesting that dCBT-I is comparably efficacious across a wide range of demographic groups. Furthermore, while differences in attrition were found based on SES, attrition did not differ between white and black participants.

conclusionsResults provide evidence that the wide dissemination of dCBT-I may effectively target both insomnia and comorbid depression across a wide spectrum of the population.

Indexed as

AdultAgedCognitive Behavioral TherapyDepressionFemaleHumansLinear ModelsMaleMichiganMiddle AgedSleep Initiation and Maintenance DisordersTelemedicineTreatment OutcomeCBT-IClinical Trial Identifier: NCT02988375Clinical Trial Registry: clinicaltrials.govdepressioninsomniaInternet

Identifiers

PMID29792241
PMCPMC7050476

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.