Evidence map›Paper›PMID 29792192›Full record

ReviewLipids in health and disease2018

Detection technologies and metabolic profiling of bile acids: a comprehensive review.

Yanan Liu, Zhihui Rong, Dong Xiang, Chengliang Zhang, Dong Liu

Open access · goldAbstract readReview
In one paragraph

Review in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. [Analysis and comparison of bile acid metabolism characteristics in children and adults with metabolic- associated fatty liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
  5. Article
  6. Frontiers in cellular and infection microbiology · 2025
    Article
  7. Elucidating Bile Acid Tolerance inFoods (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Enhancing LC/ESI-MS/MS Throughput for Plasma Bile Acid Assay by Derivatization-based Sample-Multiplexing.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2020
    Article
  18. Article
  19. Review
  20. Metabolism of obeticholic acid in brown bullhead (Ameiurus nebulosus).Environmental science and pollution research international · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yanan LiuDepartment of Pharmacy of Tongji Hospital, Tongji Medical School, Huazhong Science and Technology University, Wuhan, 430030, China.
Zhihui RongDepartment of Paediatrics of Tongji Hospital, Tongji Medical School, Huazhong Science and Technology University, Wuhan, 430030, China.
Dong XiangDepartment of Pharmacy of Tongji Hospital, Tongji Medical School, Huazhong Science and Technology University, Wuhan, 430030, China.
Chengliang ZhangDepartment of Pharmacy of Tongji Hospital, Tongji Medical School, Huazhong Science and Technology University, Wuhan, 430030, China. ph3719@aliyun.com.
Dong LiuDepartment of Pharmacy of Tongji Hospital, Tongji Medical School, Huazhong Science and Technology University, Wuhan, 430030, China. ld2069@outlook.com.
Tongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bile acids (BAs) are important regulatory factors of life activities, which are involved in the regulation of glucose, lipid and energy metabolisms, and closely associated with intestinal hormones, microbiotas and energy balance. BAs abnormalities easily lead to inflammation and metabolic diseases, in turn, the progress of diseases could influence characteristics of BAs. Therefore, accurate detection of BAs contents is of great significance to disease prevention, diagnosis and treatment. At present, the most widely used enzymatic method in clinical practice is applicable to the detection of total bile acid (TBA). In laboratory research, different types of BAs can be accurately separated and quantified by liquid chromatography-mass spectrometry (LC-MS). The metabolic profiling of BAs based on detection technologies can completely and accurately monitor their types and contents, playing a crucial role in disease prevention, diagnosis and treatment. We herein reviewed the main detection technologies of BAs and the application of metabolic profiling in related diseases in recent years.

Indexed as

AnimalsBile Acids and SaltsChromatography, LiquidEnergy MetabolismEnzyme AssaysGastrointestinal MicrobiomeHumansInflammationLipid MetabolismMass SpectrometryMetabolic DiseasesMetabolomeBile Acids and SaltsBile acidsDetection technologiesLiquid chromatography-mass spectrometryMetabolic diseaseMetabolic profiling

Identifiers

PMID29792192
PMCPMC5966875
OpenAlexW2805945275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.