Evidence map›Paper›PMID 29792186›Full record

ArticleBMC cancer2018

Involvement of the CB

Mohammed I Khan, Anna A Sobocińska, Klaudia K Brodaczewska, Katarzyna Zielniok, Malgorzata Gajewska, Claudine Kieda, Anna M Czarnecka, Cezary Szczylik

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Cannabinoids and Prostate Cancer: A Systematic Review of Animal Studies.International journal of molecular sciences · 2020
    Pooled it
  2. Article
  3. Selective CBPharmaceuticals (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Lipids as Targets for Renal Cell Carcinoma Therapy.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Cannabinoids in the landscape of cancer.Journal of cancer research and clinical oncology · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mohammed I KhanMolecular Oncology Laboratory, Department of Oncology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warsaw, Poland. imrankhanbioinfo@gmail.com.
Anna A SobocińskaMolecular Oncology Laboratory, Department of Oncology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warsaw, Poland.
Klaudia K BrodaczewskaMolecular Oncology Laboratory, Department of Oncology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warsaw, Poland.
Katarzyna ZielniokDepartment of Physiological Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159, 02-776, Warsaw, Poland.
Malgorzata GajewskaDepartment of Physiological Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159, 02-776, Warsaw, Poland.
Claudine KiedaMolecular Oncology Laboratory, Department of Oncology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warsaw, Poland.
Anna M CzarneckaMolecular Oncology Laboratory, Department of Oncology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warsaw, Poland.
Cezary SzczylikMolecular Oncology Laboratory, Department of Oncology, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warsaw, Poland.
Wojskowy Instytut Medycyny Lotniczej · PLWarsaw University of Life Sciences · PL

Funding

Narodowe Centrum Nauki (PL) UMO-2013/09/N/NZ5/02809
6 · The paper itself

Abstract

backgroundThe anti-tumor properties of cannabinoids have been investigated in many in vitro and in vivo studies. Many of these anti-tumor effects are mediated via cannabinoid receptor types 1 and 2 (CB

methodsHuman RCC cell lines were used for this study. The CB

resultsThe CB1 and CB2 genes expression was shown by real-time PCR and flow cytometric and western blot analysis indicating a higher level of CB

conclusionsThis study elucidated the involvement of CB

Indexed as

ApoptosisBenzoxazinesCannabinoid Receptor AgonistsCannabinoid Receptor AntagonistsCarcinoma, Renal CellCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorG1 Phase Cell Cycle CheckpointsHumansKidney NeoplasmsMorpholinesNaphthalenesReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Signal Transduction(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanoneBenzoxazinesCannabinoid Receptor AgonistsCannabinoid Receptor AntagonistsMorpholinesNaphthalenesReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2CB1 and CB2 receptorsEndocannabinoid system (ECS)JWH-133Renal cell carcinomaWIN 55,212–2 mesylate

Identifiers

PMID29792186
PMCPMC5966919
OpenAlexW2805882821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.