Evidence map›Paper›PMID 29792185›Full record

ArticleBMC urology2018

Assessment of the use of contrast enhanced ultrasound in guiding microdissection testicular sperm extraction in nonobstructive azoospermia.

Shijun Zhang, Jing Du, Ruhui Tian, Shaowei Xie, Fenghua Li, Zheng Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shijun ZhangDepartment of ultrasound, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian RD, Shanghai, 200127, China.
Jing DuDepartment of ultrasound, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian RD, Shanghai, 200127, China.
Ruhui TianDepartment of Andrology, Shanghai General Hospital, Shanghai Jiaotong University, 100 Haining RD, Shanghai, 200080, China.
Shaowei XieDepartment of ultrasound, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian RD, Shanghai, 200127, China.
Fenghua LiDepartment of ultrasound, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian RD, Shanghai, 200127, China. fenghuali61@163.com.ORCID http://orcid.org/0000-0001-9593-222X
Zheng LiDepartment of Andrology, Shanghai General Hospital, Shanghai Jiaotong University, 100 Haining RD, Shanghai, 200080, China.

Funding

cultivating scientific research seed plan of Renji Hospital RJZZ14-012Science and Technology Commission of Shanghai Municipality 15411966300Shanghai ability construction project of Clinical Assistant Department SHDC22015003
6 · The paper itself

Abstract

backgroundThe aim of this study is to assess the value of contrast-enhanced ultrasound (CEUS) as a new non-invasive approach to locate the testicular area in which spermatogenesis is most likely to be found in non-obstructive azoospermic testes and to evaluate the accuracy of CEUS as a predictor of successful sperm retrieval.

methodsCEUS was performed in 120 nonobstructive azoospermia (NOA) patients. Microdissection testicular sperm extraction (M-TESE) was performed on the best and poorest perfusion areas selected by CEUS and on conventional areas.

resultsIn the 187 testicles that underwent M-TESE, the sperm retrieval rates (SRRs) in the best perfusion area and poorest perfusion area over the maximal longitudinal section and conventional area were 63.1, 34.7 and 47.1%. According to receiver operating characteristic (ROC) analysis, the arrival times (AT) ≤27 s, time-to-peak intensity (TTP) ≤45 s, and peak intensity (PI) ≥11 dB were the best predictors of positive sperm retrieval. The location of the best perfusion area was able to guide M-TESE to improve the success rates.

conclusionsTesticle CEUS is suggested to be performed in all patients with NOA. If AT≤27 s, TTP ≤ 45 s or PI≥11 dB are found in the best perfusion area, M-TESE is strongly recommended.

Indexed as

Contrast MediaSperm RetrievalAdultAzoospermiaHumansMaleMicrodissectionMicrovesselsProspective StudiesTestisUltrasonography, InterventionalYoung AdultContrast MediaContrast-enhanced ultrasoundJohnson scoreMicrodissection testicular sperm extractionNon-obstructive azoospermiaThe sperm retrieval rate

Identifiers

PMID29792185
PMCPMC5966902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.