ArticleObesity surgery2018
Evidence That the Length of Bile Loop Determines Serum Bile Acid Concentration and Glycemic Control After Bariatric Surgery.
Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Optimal Small Bowel Limb Lengths of Roux-en-Y Gastric Bypass.Current obesity reports · 2023Pooled it
- Mid-Long-Term Effect of Metabolic Surgery on Type 2 Diabetes in Nonobese Patients: a Meta-analysis.Obesity surgery · 2023Pooled it
- What Is the Efficacy of Short Length of Biliopancreatic Limb in One-Anastomosis Gastric Bypass? A Systematic Review and Meta-analysis of Short-Term Results.Obesity surgery · 2022Pooled it
- Changes in fasting bile acid profiles after Roux-en-Y gastric bypass and sleeve gastrectomy.Medicine · 2021Pooled it
- Post-Bariatric Hypoglycemia: Diagnosis, Mechanisms and Management-A Case Report-Based Review.Journal of clinical medicine · 2026Review
- Association of Total Small Bowel Length with Glycaemic Control and Metabolic Syndrome in Metabolic and Bariatric Surgery Patients: A Cross-Sectional Study in a Taiwanese Cohort.Obesity surgery · 2026Article
- Robotic 3-arm Roux-en-Y gastric bypass: a feasible, safe and cost-effective approach based on patient selection.Journal of robotic surgery · 2025Article
- Mid-term Outcomes in Primary Roux-en-Y Gastric Bypass Procedures with Short or Long Biliopancreatic Limb.Obesity surgery · 2025Article
- Impact of bypass percentage on clinical outcomes following one-anastomosis gastric bypass: a one-year follow-up study.BMC surgery · 2025Article
- Reoperation After Loop Duodenojejunal Bypass with Sleeve Gastrectomy: A 9-Year Experience.Obesity surgery · 2024Article
- Increase in bile acids after sleeve gastrectomy improves metabolism by activating GPBAR1 to increase cAMP in mice with nonalcoholic fatty liver disease.Immunity, inflammation and disease · 2024Article
- OAGB Bowel Function in Patients With up to 5 Years Follow-Up: Updated Outcomes.Obesity surgery · 2024Article
- Effect of Primary Versus Revisional One Anastomosis Gastric Bypass (OAGB) on Fatty Acid Profile.Obesity surgery · 2024Article
- Research progress on the relationship between bile acid metabolism and type 2 diabetes mellitus.Diabetology & metabolic syndrome · 2023Review
- Roux-en-Y and One-Anastomosis Gastric Bypass Surgery Are Superior to Sleeve Gastrectomy in Lowering Glucose and Cholesterol Levels Independent of Weight Loss: a Propensity-Score Weighting Analysis.Obesity surgery · 2023Article
- Measures of glucose homeostasis during and after duodenal exclusion using a duodenal-jejunal bypass liner in a normoglycemic, nonobese canine model.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2022Article
- Serum free fatty acid levels and insulin resistance in patients undergoing one-anastomosis gastric bypass.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Article
- One-anastomosis gastric bypass modulates the serum levels of pro- and anti-inflammatory oxylipins, which may contribute to the resolution of inflammation.International journal of obesity (2005) · 2022Article
- Bariatric Surgery in NAFLD.Digestive diseases and sciences · 2022Review
- Variation in Small Bowel Length and Its Influence on the Outcomes of Sleeve Gastrectomy.Obesity surgery · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBariatric surgery contributes to the improvement in glucose metabolism that may be related to a postoperative increase in serum bile acids (BAs). Three commonly used types of bariatric procedures, laparoscopic sleeve gastrectomy (LSG) (without creation of a bile loop), Roux-en-Y gastric bypass (RYGB), and omega-loop gastric bypass (OLGB) (with creation of shorter 100-150 cm and longer 200-280 cm bile loops, respectively), differ in their effects on glycemic control. The aim of the study was to compare the effects of various bariatric procedures on serum BA concentration and glucose homeostasis.
methodsSerum BAs in 26 obese patients were determined by liquid chromatography-mass spectrometry prior to bariatric surgery, as well as 4 days and 3 months thereafter.
resultsFour days after the surgery, serum concentrations of BAs in LSG and OLGB groups were similar as prior to the procedure, and a slight decrease in serum BAs was observed in the RYGB group. Serum BA level in the LSG group remained unchanged also at 3 months after the surgery, whereas a significant 0.5- and 3-fold increase in this parameter was noted in the RYGB and OLGB groups, respectively. Serum concentration of BAs correlated positively with the length of the bile loop (R = 0.47, p < 0.05).
conclusionThe evident improvement of glycemic control observed 3 months after OLGB might be associated with a postoperative increase in serum BAs, resulting from their better absorption from the longer bile loop. However, the changes in serum BAs probably had little or no impact on insulin sensitivity improvement at 4 days post-surgery.
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