ReviewCurrent neurology and neuroscience reports2018
Behçet's Syndrome and Nervous System Involvement.
Review in Current neurology and neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- The effectiveness of the anti-tumor necrosis factor therapy infliximab in neuro-Behçet's disease: a systematic review and meta-analysis.The Journal of international medical research · 2023Pooled it
- Audiological and vestibular measurements in Behçet's disease.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Trial
- Granulomatous Diseases of the CNS: Aetiology, Neuroradiological Features and Clinical Findings.Clinical neuroradiology · 2026Review
- Beyond Venous Inflammation: Vessel Wall Imaging of Intracranial Arteries in Neuro-Behçet's Syndrome.European journal of neurology · 2026Article
- Neuro-behcet's syndrome: epidemiology, mechanisms, and emerging strategies in diagnosis and treatment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Review
- Evaluation of optic disc and parafoveal parameters in Neuro-Behçet patients without ocular involvement using optical coherence tomography angiography.International ophthalmology · 2025Article
- Demographics and clinical manifestations in patients with Behçet's disease: a retrospective observational study from a non-endemic country.Rheumatology international · 2025Observational
- Neuro-Behçet's disease: an update of clinical diagnosis, biomarkers, and immunopathogenesis.Clinical and experimental immunology · 2025Review
- Mimickers of nervous system involvement among patients with Behçet's syndrome.Journal of neurology · 2024Article
- Article
- Neurologic manifestations of Behçet disease: rheumatology experience.Zeitschrift fur Rheumatologie · 2024Article
- Clinical features of Behçet's disease and prediction of the use of biologics in 488 cases: a single tertiary center study.Rheumatology international · 2023Article
- Diagnosis and management of Neuro-Behçet disease with isolated intracranial hypertension: a case report and literature review.BMC neurology · 2023Review
- Autoimmune diseases of the brain, imaging and clinical review.The neuroradiology journal · 2022Review
- Neuro-Behçet - Clinical and radiological findings in a Patient of Sub-saharan African origin.Radiology case reports · 2022Article
- Behçet syndrome.Nature reviews. Disease primers · 2021Review
- Characteristics and phenotype heterogeneity in late-onset Behçet's syndrome: a cohort from a referral center in China.Clinical rheumatology · 2021Article
- Quality of life in neuro-Behçet's disease: a cross-sectional study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Cluster analysis of phenotypes of patients with Behçet's syndrome: a large cohort study from a referral center in China.Arthritis research & therapy · 2021Article
- Optic neuritis as a presenting feature of Behçet's disease: case-based review.Rheumatology international · 2021Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewAlthough Behçet's syndrome (BS) is classified as a rare disease in European countries and the USA, its neurologic involvement "neuro-Behçet's syndrome (NBS)" is commonly included in the differential diagnosis of many inflammatory and vascular central nervous system (CNS) disorders. Clinical and neuroimaging findings support two major forms of NBS: parenchymal NBS (p-NBS) and an extra-parenchymal form that presents with cerebral venous sinus thrombosis (CVST). The present review summarizes recent findings on the etiopathogenesis and clinico-radiological features of this disorder as well as its treatment options. RECENT
findingsRecent laboratory and clinical findings include the discovery of antibodies to human and mouse neuro-fibrils showing cross-reactivity with Streptococcus spp. and Mycobacterium tuberculosis heat shock proteins (HSP) in NBS. Diagnostically, two distinct magnetic resonance imaging (MRI) patterns of spinal cord involvement have been observed: (a) "Bagel sign" and (b) "motor neuron" patterns. Therapeutic studies have shown that infliximab effectively prevents further relapses and stabilizes the symptoms of patients experiencing ongoing clinical relapses while being treated with single or multiple immunosuppressant drugs. Primary neurological involvement referred to as NBS. The majority of patients with NBS present with parenchymal involvement that commonly affects the brain stem-diencephalic region. Headache, dysarthria, ataxia, and hemiparesis are the main clinical features of NBS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.