ArticleActa diabetologica2018
The association between age at menarche and later risk of gestational diabetes is mediated by insulin resistance.
Article in Acta diabetologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Pubertal timing in boys and girls born to mothers with gestational diabetes mellitus: a systematic review.European journal of endocrinology · 2021Pooled it
- Age at menarche and the future risk of gestational diabetes: a systematic review and dose response meta-analysis.Acta diabetologica · 2018Pooled it
- Associations Between Prepregnancy Menstrual Characteristics, Age at Menarche, and the Risk of Gestational Diabetes Mellitus: A Matched Case-Control Study.Journal of diabetes research · 2026Observational
- Early-life menstrual characteristics and gestational diabetes in a large US cohort.Paediatric and perinatal epidemiology · 2024Article
- Development and Validation of Risk Prediction Models for Gestational Diabetes Mellitus Using Four Different Methods.Metabolites · 2022Article
- Risk Factors Screening for Gestational Diabetes Mellitus Heterogeneity in Chinese Pregnant Women: A Case-Control Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Temporal trends without seasonal effects on gestational diabetes incidence relate to reductions in indices of insulin secretion: the Cambridge Baby Growth Study.Acta diabetologica · 2019Article
- Age at Menarche and Blood Pressure in Pregnancy.Pregnancy hypertension · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
aimsAssociations have been reported between age at menarche and the later risk of gestational diabetes. However, it is not known whether these associations reflect differences in insulin sensitivity and/or pancreatic β-cell function in pregnancy.
methodsWe examined this question in women enrolled in the prospective Cambridge Baby Growth Study who recalled their age at menarche in questionnaires during pregnancy. Polynomial logistic and linear regression models were used to relate menarche timing to the risk of gestational diabetes, both unadjusted and adjusted for the Homeostasis Model Assessments of insulin resistance (HOMA IR) and pancreatic β-cell function (HOMA B) at week 28 of pregnancy.
resultsAge at menarche showed a U-shaped association with gestational diabetes risk (linear term: p = 9.5 × 10
conclusionsThese results suggest that the associations between age at menarche and risk of gestational diabetes and raised pregnancy glucose concentrations may be mediated by insulin resistance.
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