Evidence map›Paper›PMID 29789941›Full record

ArticleArchives of virology2018

New variants of porcine epidemic diarrhea virus with large deletions in the spike protein, identified in the United States, 2016-2017.

Yunfang Su, Yixuan Hou, Melanie Prarat, Yan Zhang, Qiuhong Wang

Abstract read
In one paragraph

Article in Archives of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
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  11. Risk and Mitigation of African Swine Fever Virus in Feed.Animals : an open access journal from MDPI · 2021
    Review
  12. Article
  13. Review
  14. Molecular Characteristics and Pathogenicity ofFrontiers in veterinary science · 2020
    Article
  15. Article
  16. Review
  17. Article
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  19. Article
  20. Genetic evolution analysis and pathogenicity assessment of porcine epidemic diarrhea virus strains circulating in part of China during 2011-2017.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunfang SuThe Ohio State University, Wooster, Ohio, USA.
Yixuan HouThe Ohio State University, Wooster, Ohio, USA.
Melanie PraratOhio Department of Agriculture, 8995 East Main Street Building #6, Reynoldsburg, OH, 43068, USA.
Yan ZhangOhio Department of Agriculture, 8995 East Main Street Building #6, Reynoldsburg, OH, 43068, USA. yan.zhang@agri.ohio.gov.
Qiuhong WangFood Animal Health Research Program, Ohio Agricultural Research and Development Center, College of Food, Agricultural and Environmental Sciences; Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Wooster, Ohio, USA. wang.655@osu.edu.ORCID http://orcid.org/0000-0002-8238-417X

Funding

National Institute of Food and Agriculture, U.S. Department of Agriculture 2015-67015-23067
6 · The paper itself

Abstract

Four types of porcine epidemic diarrhea virus (PEDV) variants with a large deletion in the spike protein were detected, together with the original US PEDV, from pig fecal and oral fluid samples collected during 2016-2017 in the US. Two of the variants are similar to those identified in Japan: one contains a 194-aa deletion, the same as PEDV variant TTR-2/JPN/2014, while the other contains a 204-aa deletion, the same as PEDV variant JKa-292/CS1de204. Two new S1 NTD-del PEDV variants were found: one contains a 201-aa deletion located at residues 30-230 and the other contains a 202-aa deletion located at residues 24-225 of the S protein. This is the first report on coinfection of S1 NTD-del PEDV variants and the original US PEDV strain in US pigs, indicating that PEDV continues to evolve in pigs and might be responsible for disease pattern changes.

Indexed as

GenotypeSequence DeletionAnimalsBase SequenceCoronavirus InfectionsFarmsFecesIncidenceMolecular TypingPhylogenyPorcine epidemic diarrhea virusRNA, ViralSpike Glycoprotein, CoronavirusSwineSwine DiseasesUnited StatesRNA, ViralSpike Glycoprotein, Coronavirus

Identifiers

PMID29789941
PMCPMC7087112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.