Evidence map›Paper›PMID 29789912›Full record

ArticleEuropean radiology2018

Meniscal pathologies on MRI correlate with increased bone tracer uptake in SPECT/CT.

Jan Rechsteiner, Michael T Hirschmann, Milos Dordevic, Anna L Falkowski, Enrique A Testa, Felix Amsler, Anna Hirschmann

Abstract read
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In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Beyond the ACL: The Hidden Impact of Ramp Tears on Knee Stability.The archives of bone and joint surgery · 2026
    Review
  2. Early knee OA definition-what do we know at this stage? An imaging perspective.Therapeutic advances in musculoskeletal disease · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jan RechsteinerDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland Bruderholz, 4101, Binningen, Switzerland.
Michael T HirschmannDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland Bruderholz, 4101, Binningen, Switzerland.
Milos DordevicDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland Bruderholz, 4101, Binningen, Switzerland.
Anna L FalkowskiDepartment of Radiology, Kantonsspital Baselland Bruderholz, 4101, Binningen, Switzerland.
Enrique A TestaDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland Bruderholz, 4101, Binningen, Switzerland.
Felix AmslerAmsler Consulting, Gundeldingerrain 111, 4059, Basel, Switzerland.
Anna HirschmannDepartment of Radiology and Nuclear Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland. anna.hirschmann@usb.ch.ORCID http://orcid.org/0000-0003-1560-0247
Kantonsspital Baselland Standort Bruderholz · CHUniversity Hospital of Basel · CHMettler-Toledo (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the relationship of subchondral bone tracer uptake (BTU) on SPECT/CT and meniscal pathologies on MRI in patients with painful knees.

methodsTwenty-five patients who had MRI and SPECT/CT within 3 months without knee surgery or grade ≥3 cartilage lesions were prospectively included. Maximum values of each subchondral femorotibial area were quantified and a ratio was calculated in relation to a femoral shaft reference region, which represented the BTU background activity. Meniscal lesions were graded (intact/degeneration/tear) and meniscal extrusion (no/yes) was assessed using MRI by two musculoskeletal radiologists blinded to the SPECT/CT findings. One-tailed Spearman correlations served for statistics (p < 0.05).

resultsKnees with meniscal degeneration or tear showed a significantly higher BTU in the medial femorotibial compartment (p = 0.045) when compared to intact menisci. Meniscal degeneration was associated with an increased BTU in the lateral femorotibial compartment; however, this was not statistically significant (p = 0.143). Patients with an extruded meniscus showed significantly higher BTU compared to a non-extruded meniscus (p < 0.020).

conclusionsMedial femorotibial BTU in SPECT/CT was associated with meniscal pathologies. Highest BTU was found in patients with meniscal tears. SPECT/CT appears to be a useful imaging modality to identify patients with overloading or early osteoarthritis. KEY POINTS: • Meniscal degeneration and tears correlate significantly with increased BTU using SPECT/CT. • Medial meniscus extrusion is associated with an increased BTU in SPECT/CT. • SPECT/CT allows detection of overloading and early osteoarthritis.

Indexed as

AdultAgedArthralgiaFemaleFollow-Up StudiesHumansKnee JointMagnetic Resonance ImagingMaleMenisci, TibialMeniscusMiddle AgedOsteoarthritis, KneePositron Emission Tomography Computed TomographyProspective StudiesRadiopharmaceuticalsRadiopharmaceuticalstechnetium Tc 99m hydroxymethylene diphosphonateTechnetium Tc 99m MedronateKnee injuriesMagnetic resonance imagingMeniscusOsteoarthritisSingle photon emission computed tomography/computed tomography

Identifiers

PMID29789912
OpenAlexW2803861953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.