ArticleCardiovascular and interventional radiology2018
CT Angiography in the Lower Extremity Peripheral Artery Disease Feasibility of an Ultra-Low Volume Contrast Media Protocol.
Article in Cardiovascular and interventional radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 44 citations in OpenAlex.
- Halved contrast medium dose in lower limb dual-energy computed tomography angiography-a randomized controlled trial.European radiology · 2023Trial
- Radiation dose and image quality with new protocol in lower extremity computed tomography angiography.La Radiologia medica · 2019Trial
- Feasibility of 80-kVp CTA with reduced iodine contrast in chronic limb-threatening ischemia.Medicine · 2026Article
- A narrative review of imaging misallocation in peripheral artery disease: a value-based medicine perspective.Cardiovascular diagnosis and therapy · 2025Review
- Quantifying lower extremity blood flow using low-dose CT perfusion: validation in a swine model.Radiology advances · 2024Article
- Utilization of double contrast-enhancement boost for lower-extremity CT angiography.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Use of ultra-low contrast dose CT aortography for the management of aortic aneurysmal disease.Journal of cardiothoracic surgery · 2024Article
- Concurrent Chronic Exertional Compartment Syndrome and Popliteal Artery Entrapment Syndrome.Diagnostics (Basel, Switzerland) · 2024Article
- How subjective CT image quality assessment becomes surprisingly reliable: pairwise comparisons instead of Likert scale.European radiology · 2024Article
- Evaluating the risk of return to the operating room across all elective orthopaedic procedures.Journal of orthopaedic surgery and research · 2024Article
- The Clinical Utility of Lower Extremity Dual-Energy CT Angiography in the Detection of Bone Marrow Edema in Diabetic Patients with Peripheral Artery Disease.Journal of clinical medicine · 2024Article
- Advanced virtual monoenergetic imaging algorithm for lower extremity computed tomography angiography: effects on image quality, artifacts, and peripheral arterial disease evaluationDiagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Low-iodine 40-keV virtual monoenergetic CT angiography of the lower extremities.Frontiers in cardiovascular medicine · 2023Article
- Imaging Findings of Peripheral Arterial Disease on Lower-Extremity CT Angiography Using a Virtual Monoenergetic Imaging Algorithm.Journal of the Korean Society of Radiology · 2022Review
- The impact of the field of view (FOV) on image quality in MDCT angiography of the lower extremities.European radiology · 2022Article
- Lower extremity CT angiography in peripheral arterial disease: from the established approach to evolving technical developments.The international journal of cardiovascular imaging · 2021Review
- Quick evaluation of lower leg ischemia in patients with peripheral arterial disease by time maximum intensity projection CT angiography: a pilot study.BMC medical imaging · 2021Article
- CT angiography for pulmonary embolism in the emergency department: investigation of a protocol by 20 ml of high-concentration contrast medium.La Radiologia medica · 2020Article
- Image quality and radiation exposure with low-contrast-dose computed tomography angiography of the lower extremities.Polish journal of radiology · 2020Article
- Computed Tomography Angiography in Peripheral Arterial Disease: Comparison of Three Image Acquisition Techniques to Optimize Vascular Enhancement-Randomized Controlled Trial.Frontiers in cardiovascular medicine · 2020Article
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Authors and funding
8 authors at 3 institutions in 4 countries.
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Abstract
purposeThe ALARA principle is not only relevant for effective dose (ED) reduction, but also applicable for contrast media (CM) management. Therefore, the aim was to evaluate the feasibility of an ultra-low CM protocol in the assessment of peripheral artery disease (PAD). MATERIALS AND
methodsFifty PAD patients were scanned on third-generation dual-source computed tomography, from diaphragm to the forefoot, as follows: tube voltage: 70 kV, reference effective tube current: 90 mAs, collimation: 192 × 2 × 0.6 mm, with individualized acquisition timing. The protocol ED (mSv) was quantified with dedicated software. CM protocol consisted of 15 ml test bolus and 30 ml main bolus (300 mgI/ml) injected at 5 ml/s, followed by a 40 ml saline chaser at the same flow rate. Aorto-popliteal bolus transit time was used to calculate the overall acquisition time and delay. Objective (hounsfield units-HU; contrast-to-noise ratio-CNR) and subjective image quality (four-point Likert score) were assessed at different anatomical regions from the aorta down to the forefoot.
resultsMean attenuation values were exceeding 250 HU from aorta down to the anterior tibial artery with CNR < 13. However, decline in attenuation was observed in more distal region with mean values of 165 and 199 HU, in left and right dorsalis pedis artery, respectively. Mode subjective image quality from the level of aorta down to the popliteal segment was excellent; below the knee mode score was good. The mean ED per protocol was 1.1 ± 0.5 mSv.
conclusionUse of an ultra-low CM volume protocol at 70 kV is feasible in the evaluation of PAD, resulting in good to excellent image quality with mean ED of 1.1 ± 0.5 mSv. LEVEL OF EVIDENCE: Level 3, Local non-random sample.
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