Evidence map›Paper›PMID 29789614›Full record

ArticleNature communications2018

Augmenting the Calvin-Benson-Bassham cycle by a synthetic malyl-CoA-glycerate carbon fixation pathway.

Hong Yu, Xiaoqian Li, Fabienne Duchoud, Derrick S Chuang, James C Liao

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 144 citations in OpenAlex.

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  15. New-to-nature CONature communications · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hong YuUCLA-DOE Institute of Genomics and Proteomics, 420 Westwood Plaza, Los Angeles, CA, 90095, USA.
Xiaoqian LiDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA, 90095, USA.
Fabienne DuchoudDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA, 90095, USA.
Derrick S ChuangDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA, 90095, USA.
James C LiaoAcademia Sinica, 128 Academia Road, Section 2, 115, Taipei, Taiwan. liaoj@ucla.edu.
University of California, Los Angeles · USAcademia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Calvin-Benson-Bassham (CBB) cycle is presumably evolved for optimal synthesis of C3 sugars, but not for the production of C2 metabolite acetyl-CoA. The carbon loss in producing acetyl-CoA from decarboxylation of C3 sugar limits the maximum carbon yield of photosynthesis. Here we design a synthetic malyl-CoA-glycerate (MCG) pathway to augment the CBB cycle for efficient acetyl-CoA synthesis. This pathway converts a C3 metabolite to two acetyl-CoA by fixation of one additional CO

Indexed as

Acetyl Coenzyme AAcyl Coenzyme ABacterial ProteinsCarbon DioxideEscherichia coliGlyceric AcidsGlyoxylatesMetabolic EngineeringPhotosynthesisSynechococcusTransgenesAcetyl Coenzyme AAcyl Coenzyme ABacterial ProteinsCarbon DioxideGlyceric AcidsGlyoxylatesglyoxylic acidmalyl-coenzyme A

Identifiers

PMID29789614
PMCPMC5964204
OpenAlexW2804527372

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.