Evidence map›Paper›PMID 29789578›Full record

ArticleCell death & disease2018

SK channel activation is neuroprotective in conditions of enhanced ER-mitochondrial coupling.

Birgit Honrath, Inge E Krabbendam, Carmen IJsebaart, Valentina Pegoretti, Nadia Bendridi, Jennifer Rieusset, Martina Schmidt, Carsten Culmsee, Amalia M Dolga

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Birgit HonrathInstitute of Pharmacology and Clinical Pharmacy, University of Marburg, 35043, Marburg, Germany. birgithonrath@gmail.com.
Inge E KrabbendamFaculty of Science and Engineering, Groningen Research Institute of Pharmacy (GRIP), Research School of Behavioural and Cognitive Neurosciences (BCN), Department of Molecular Pharmacology, University of Groningen, 9713 AV, Groningen, The Netherlands.
Carmen IJsebaartFaculty of Science and Engineering, Groningen Research Institute of Pharmacy (GRIP), Research School of Behavioural and Cognitive Neurosciences (BCN), Department of Molecular Pharmacology, University of Groningen, 9713 AV, Groningen, The Netherlands.
Valentina PegorettiFaculty of Science and Engineering, Groningen Research Institute of Pharmacy (GRIP), Research School of Behavioural and Cognitive Neurosciences (BCN), Department of Molecular Pharmacology, University of Groningen, 9713 AV, Groningen, The Netherlands.
Nadia BendridiINSERM U1060, INRA U1235, Laboratoire CarMeN, Lyon University, Université Claude Bernard Lyon1, INSA-Lyon, F-69921, Oullins, France.
Jennifer RieussetINSERM U1060, INRA U1235, Laboratoire CarMeN, Lyon University, Université Claude Bernard Lyon1, INSA-Lyon, F-69921, Oullins, France.
Martina SchmidtFaculty of Science and Engineering, Groningen Research Institute of Pharmacy (GRIP), Research School of Behavioural and Cognitive Neurosciences (BCN), Department of Molecular Pharmacology, University of Groningen, 9713 AV, Groningen, The Netherlands.
Carsten CulmseeInstitute of Pharmacology and Clinical Pharmacy, University of Marburg, 35043, Marburg, Germany.ORCID 0000-0002-5121-5015
Amalia M DolgaInstitute of Pharmacology and Clinical Pharmacy, University of Marburg, 35043, Marburg, Germany. a.m.dolga@rug.nl.
University of Groningen · NLPhilipps University of Marburg · DEUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in the strength and interface area of contact sites between the endoplasmic reticulum (ER) and mitochondria contribute to calcium (Ca

Indexed as

Ion Channel GatingNeuroprotectionAnimalsCalciumCell DeathCell RespirationCell SurvivalEndoplasmic ReticulumHEK293 CellsHumansMiceMitochondriaNeuronsSmall-Conductance Calcium-Activated Potassium ChannelsCalciumSmall-Conductance Calcium-Activated Potassium Channels

Identifiers

PMID29789578
PMCPMC5964177
OpenAlexW2804648348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.