Evidence map›Paper›PMID 29789577›Full record

ArticleCell death & disease2018

Long non-coding RNA Gm2199 rescues liver injury and promotes hepatocyte proliferation through the upregulation of ERK1/2.

Qiang Gao, Yunyan Gu, Yanan Jiang, Li Fan, Zixiang Wei, Haobin Jin, Xirui Yang, Lijuan Wang, Xuguang Li, Sheng Tai and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Deciphering the role ofWorld journal of hepatology · 2025
    Review
  3. MedComm · 2023
    Article
  4. Decoding the regulatory roles of non-coding RNAs in cellular metabolism and disease.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Review
  5. Article
  6. The activation of MActa biochimica et biophysica Sinica · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Qiang GaoDepartment of Physiology, Harbin Medical University, 150081, Harbin, China.
Yunyan GuCollege of Bioinformatics Science and Technology, Harbin Medical University, 150081, Harbin, China.
Yanan JiangDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine and Pharmaceutics), Harbin Medical University, 150081, Harbin, China.
Li FanDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine and Pharmaceutics), Harbin Medical University, 150081, Harbin, China.
Zixiang WeiDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine and Pharmaceutics), Harbin Medical University, 150081, Harbin, China.
Haobin JinDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine and Pharmaceutics), Harbin Medical University, 150081, Harbin, China.
Xirui YangDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine and Pharmaceutics), Harbin Medical University, 150081, Harbin, China.
Lijuan WangDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine and Pharmaceutics), Harbin Medical University, 150081, Harbin, China.
Xuguang LiDepartment of Materia Medica (State Key Laboratory of Bioactive Substance and Function of Natural Medicines), Chinese Academy of Medical Sciences and Peking Union Medical College, 100050, Beijing, China.
Sheng TaiDepartment of General Surgery, The Second Affiliated Hospital of Harbin Medical University, 150001, Harbin, China.
Baofeng YangDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine and Pharmaceutics), Harbin Medical University, 150081, Harbin, China.ORCID 0000-0002-0125-1608
Yan LiuDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine and Pharmaceutics), Harbin Medical University, 150081, Harbin, China. Liuyan_gyp@163.com.
Harbin Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) are a new class of regulators of various human diseases. This study was designed to explore the potential role of lncRNAs in experimental hepatic damage. In vivo hepatic damage in mice and in vitro hepatocyte damage in AML12 and NCTC1469 cells were induced by carbon tetrachloride (CCl

Indexed as

AnimalsCell LineCell ProliferationCell SurvivalDisease Models, AnimalDown-RegulationExtracellular Signal-Regulated MAP KinasesGene OntologyGene Regulatory NetworksHepatocytesLiverMaleMice, Inbred ICRRNA, Long NoncodingRNA, MessengerUp-RegulationExtracellular Signal-Regulated MAP KinasesRNA, Long NoncodingRNA, Messenger

Identifiers

PMID29789577
PMCPMC5964236
OpenAlexW2803406156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.