Evidence map›Paper›PMID 29789437›Full record

ArticleThe Journal of cell biology2018

Dynamics of RecA-mediated repair of replication-dependent DNA breaks.

Vincent Amarh, Martin A White, David R F Leach

Open access · hybridAbstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Codeine dysregulates ribosome biogenesis inFuture drug discovery · 2023
    Article
  6. The RecA-directed recombination pathway of natural transformation initiates at chromosomal replication forks in the pneumococcus.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. SMC protein RecN drives RecA filament translocation for in vivo homology search.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Article
  10. Review
  11. Zooming in on chromosome dynamics.Cell cycle (Georgetown, Tex.) · 2020
    Review
  12. Review
  13. Article
  14. Article
  15. Recombination of the Phase-VariableJournal of bacteriology · 2019
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vincent AmarhInstitute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK.ORCID 0000-0002-6681-8118
Martin A WhiteInstitute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK.
David R F LeachInstitute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK D.Leach@ed.ac.uk.ORCID 0000-0003-4964-6913
University of Edinburgh · GB

Funding

Medical Research Council MR/M019160/1
6 · The paper itself

Abstract

Chromosomal replication is the major source of spontaneous DNA double-strand breaks (DSBs) in living cells. Repair of these DSBs is essential for cell viability, and accuracy of repair is critical to avoid chromosomal rearrangements. Repair of replication-dependent DSBs occurs primarily by homologous recombination with a sister chromosome. However, this reaction has never been visualized at a defined chromosomal locus, so little is known about its spatial or temporal dynamics. Repair of a replication-independent DSB generated in

Indexed as

DNA Breaks, Double-StrandedCell SurvivalChromosomes, BacterialDNA RepairDNA ReplicationEscherichia coliHomologous RecombinationLac OperonRec A RecombinasesRec A Recombinases

Identifiers

PMID29789437
PMCPMC6028544
OpenAlexW2804730182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.