Evidence map›Paper›PMID 29789366›Full record

ArticlemBio2018

Loss of Upc2p-Inducible

Arturo Luna-Tapia, Hubertine M E Willems, Josie E Parker, Hélène Tournu, Katherine S Barker, Andrew T Nishimoto, P David Rogers, Steven L Kelly, Brian M Peters, Glen E Palmer

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Impact ofmSphere · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Molecular Evaluation of the mRNA Expression of theJournal of fungi (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Pathogens (Basel, Switzerland) · 2020
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Loss of C-5 Sterol Desaturase Activity inAntimicrobial agents and chemotherapy · 2019
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Arturo Luna-Tapia *Department of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Hubertine M E Willems *Department of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Josie E ParkerInstitute of Life Science, Swansea University Medical School, Swansea, Wales, United Kingdom.
Hélène TournuDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Katherine S BarkerDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Andrew T NishimotoDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
P David RogersDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Steven L KellyInstitute of Life Science, Swansea University Medical School, Swansea, Wales, United Kingdom.
Brian M PetersDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Glen E PalmerDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA gpalmer5@uthsc.edu.
University of Tennessee Health Science Center · USSwansea University · GB

Funding

Novel Azole Resistance Mechanisms in Candida albicansR01AI058145 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P. DAVID · 2005 to 2021
$5.8M
Candidalysin: a key mediator of Candida vaginitis immunopathologyR01AI134796 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Brian M Peters · 2018 to 2026
$2.9M
Molecular and chemical validation of the vacuole as a new antifungal targetR01AI099080 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PALMER, GLEN · 2014 to 2018
$1.9M
A novel role for the inflammasome in the immunopathogenesis of Candida vaginitisK22AI110541 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PETERS, BRIAN M · 2016 to 2017
$268k
NIAID NIH HHS K22 AI110541NIAID NIH HHS R01 AI058145NIAID NIH HHS R01 AI099080NIAID NIH HHS R01 AI134796
6 · The paper itself

Abstract

Inactivation of sterol Δ

Indexed as

Drug Resistance, FungalAnimalsAntifungal AgentsAzolesCandida albicansCandidiasisFemaleFungal ProteinsGene Expression Regulation, FungalHumansMiceMice, Inbred C57BLMicrobial Sensitivity TestsOxidoreductasesTrans-ActivatorsVirulenceAntifungal AgentsAzolesFungal ProteinsOxidoreductasesTrans-Activatorsazole resistanceCandida albicansdisseminated candidiasisERG3mouse modelspathogenesisvaginal candidiasis

Identifiers

PMID29789366
PMCPMC5964354
OpenAlexW2803110100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.