Evidence map›Paper›PMID 29789355›Full record

ArticleJournal of lipid research2018

HDL functionality and cardiovascular outcome among nondialysis chronic kidney disease patients.

Kathrin Untersteller, Sabine Meissl, Markus Trieb, Insa E Emrich, Adam M Zawada, Michael Holzer, Eva Knuplez, Danilo Fliser, Gunnar H Heine, Gunther Marsche

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. HDL and Kidney Diseases.Advances in experimental medicine and biology · 2022
    Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Kidney as modulator and target of "good/bad" HDL.Pediatric nephrology (Berlin, Germany) · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Kathrin UnterstellerInternal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.
Sabine MeisslOtto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria.
Markus TriebOtto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria.
Insa E EmrichInternal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.
Adam M ZawadaInternal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.
Michael HolzerOtto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria.
Eva KnuplezOtto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria.
Danilo FliserInternal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.
Gunnar H HeineInternal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany gunnar.heine@uks.eu gunther.marsche@medunigraz.at.
Gunther MarscheOtto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria gunnar.heine@uks.eu gunther.marsche@medunigraz.at.ORCID 0000-0002-2422-5381
Medical University of Graz · ATSaarland University · DE

Funding

Austrian Science Fund FWF P 22976
6 · The paper itself

Abstract

CVD remains the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). CKD profoundly affects HDL composition and functionality, but whether abnormal HDL independently contributes to cardiovascular events in CKD patients remains elusive. In the present study, we assessed whether compositional and functional properties of HDL predict cardiovascular outcome among 526 nondialysis CKD patients who participate in the CARE FOR HOMe study. We measured HDL cholesterol, the content of HDL-associated proinflammatory serum amyloid A (SAA), and activities of the HDL enzymes paraoxonase and lipoprotein-associated phospholipase A2 (Lp-PLA

Indexed as

AftercareAgedCardiovascular DiseasesCholesterol, HDLCohort StudiesFemaleHumansMaleMiddle AgedRenal Insufficiency, ChronicCholesterol, HDLantioxidative activitycardiovascular eventscholesterol efflux capacityHDL functionparaoxonase activity

Identifiers

PMID29789355
PMCPMC6027904
OpenAlexW2804198857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.