ArticleJournal of epidemiology and community health2018
Maternal polycystic ovarian syndrome and offspring growth: the Upstate KIDS Study.
Article in Journal of epidemiology and community health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Fertility treatment and cardio-metabolic risk factors in middle childhood.Reproductive biomedicine online · 2025Article
- PCOS - the many faces of a disorder in women and men.Journal of endocrinological investigation · 2025Review
- Maternal self-reported polycystic ovary syndrome with offspring and maternal cardiometabolic outcomes.Human reproduction (Oxford, England) · 2024Article
- Maternal Polycystic Ovary Syndrome and the Risk of Early Childhood Obesity in Female Offspring: A Nationwide Population-Based Study.Journal of Korean medical science · 2023Article
- Association of PCOS with offspring morbidity: a longitudinal cohort study.Human reproduction (Oxford, England) · 2022Article
- Association between maternal polycystic ovary syndrome and early childhood growth: a continuous observation from 3 months to 6 years of age.Journal of assisted reproduction and genetics · 2022Article
- Cardiovascular disease risk in offspring of polycystic ovary syndrome.Frontiers in endocrinology · 2022Review
- Association of maternal polycystic ovary syndrome or anovulatory infertility with obesity and diabetes in offspring: a population-based cohort study.Human reproduction (Oxford, England) · 2021Article
- Polycystic Ovary Syndrome: Impact of Lipotoxicity on Metabolic and Reproductive Health.Obstetrical & gynecological survey · 2019Article
- Child Health: Is It Really Assisted Reproductive Technology that We Need to Be Concerned About?Seminars in reproductive medicine · 2018Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPolycystic ovarian syndrome (PCOS) is the most common cause of female infertility and is associated with higher levels of circulating androgens. Exposure to higher levels of androgens in utero may be a risk factor for obesity among children of women with PCOS.
methodsWe examined whether maternal PCOS was associated with differences in offspring growth and obesity in the Upstate KIDS study, a prospective cohort study of infants born in New York State (excluding New York City) oversampled for fertility treatments and multiple births. Measurements of offspring length/height and weight were recorded at doctor's visits through 3 years of age. PCOS diagnosis was self-reported by mothers at baseline. We used linear mixed models with robust SEs to estimate differences in growth by maternal PCOS exposure. We used logistic regression to examine whether infants experienced rapid weight gain at 4, 9 and 12 months. Growth measures were reported by 4098 mothers for 4949 children (1745 twins). Of these, 435 mothers (10.6%) had a diagnosis of PCOS.
resultsCompared with children born to mothers without PCOS, children of mothers with PCOS did not have significant differences in weight (4.81 g, 95% CI -95.1 to 104.7), length/height (0.18 cm, 95% CI -0.16 to 0.52) and body mass index (-0.14 kg/m
conclusionsOverall, we found little evidence to suggest that maternal PCOS influences early childhood growth in this large, prospective cohort study.
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