Evidence map›Paper›PMID 29789305›Full record

ArticleBMJ case reports2018

Ro-positive interstitial lung disease treated with cyclophosphamide.

Nader Habib Bedwani, Natasha Jefferson, Christopher Marguerie, Jayanta Mukherjee

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nader Habib BedwaniUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.ORCID http://orcid.org/0000-0001-7302-9355
Natasha JeffersonDepartment of Radiology, Warwick Hospital, Warwick, UK.
Christopher MarguerieDepartment of Rheumatology, Warwick Hospital, Warwick, UK.
Jayanta MukherjeeDepartment of Respiratory Medicine, Warwick Hospital, Warwick, UK.
Warwick Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial lung disease (ILD) comprises a spectrum of conditions involving inflammation and/or fibrosis of the alveolar wall causing limitation in gaseous exchange. Treatment varies depending on the underlying ILD. We describe the case of a woman presenting with a productive cough who was diagnosed with community-acquired pneumonia. While on the ward she developed type-1 respiratory failure requiring continuous positive airway pressure and intensive care unit admission. Failing to respond to targeted antimicrobials she was investigated by chest high-resolution CT and autoantibody screen to identify non-infective causes of her respiratory signs and symptoms. These demonstrated diffuse ground-glass change with peripheral honeycombing in keeping with fibrosis and alveolitis alongside high titres of anti-SS-A/Ro antibodies. She was managed with reducing course of steroids and immunosuppression with cyclophosphamide. The rational of long-term immunosuppression was based on a presumed diagnosis of lung-dominant connective tissue disease, a disease concept proposed in contemporary medical literature.

Indexed as

AgedAnti-Bacterial AgentsAntibodies, AntinuclearAnti-Inflammatory AgentsConnective Tissue DiseasesCyclophosphamideDrug Therapy, CombinationFemaleHumansHydrocortisoneImmunosuppressive AgentsLung Diseases, InterstitialPrednisoloneTomography, X-Ray ComputedAnti-Bacterial AgentsAntibodies, AntinuclearAnti-Inflammatory AgentsCyclophosphamideHydrocortisoneImmunosuppressive AgentsPrednisoloneSS-A antibodiesconnective tissue diseaseinterstitial lung diseaserespiratory system

Identifiers

PMID29789305
PMCPMC5965771
OpenAlexW2803471575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.