Evidence map›Paper›PMID 29789199›Full record

SynthesisJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia2018

Survival after in-hospital cardiac arrest among cerebrovascular disease patients.

Corey R Fehnel, Alissa Trepman, Dale Steele, Muhib A Khan, Brian Silver, Susan L Mitchell

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Corey R FehnelHebrew SeniorLife, Institute for Aging Research, Beth Israel Deaconess Medical Center, Harvard Medical School, 1200 Centre Street, Boston, MA 02131, United States. Electronic address: cfehnel@bidmc.harvard.edu.
Alissa TrepmanBrown University School of Public Health, Providence, RI, United States.
Dale SteeleBrown University School of Public Health, Center for Evidence Synthesis in Health, Providence, RI, United States.
Muhib A KhanMichigan State University College of Human Medicine, Neuroscience Institute, Division of Neurology, Spectrum Health, East Lansing, MI, United States.
Brian SilverUniversity of Massachusetts Medical School, Worcester, MA, United States. Electronic address: Brian.Silver@umassmed.edu.
Susan L MitchellHebrew SeniorLife Institute for Aging Research, Boston, MA, United States. Electronic address: smitchell@hsl.harvard.edu.
Brown University · USBeth Israel Deaconess Medical Center · USHebrew SeniorLife · USMichigan State University · USUniversity of Massachusetts Chan Medical School · US

Funding

Midcareer Mentoring Award for Patient-Oriented Research in AgingK24AG033640 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI MITCHELL, SUSAN L · 2009 to 2018
$1.8M
NIA NIH HHS K24 AG033640
6 · The paper itself

Abstract

Stroke is a leading cause of death and disability, and while preferences for cardiopulmonary resuscitation (CPR) are frequently discussed, there is limited evidence detailing outcomes after CPR among acute cerebrovascular neurology (inclusive of stroke, subarachnoid hemorrhage (SAH)) patients. Systematic review and meta-analysis of PubMed and Cochrane libraries from January 1990 to December 2016 was conducted among stroke patients undergoing in-hospital CPR. Primary data from studies meeting inclusion criteria at two levels were extracted: 1) studies reporting survival to hospital discharge after CPR with cerebrovascular primary admitting diagnosis, and 2) studies reporting survival to hospital discharge after CPR with cerebrovascular comorbidity. Meta-analysis generated weighted, pooled survival estimates for each population. Of 818 articles screened, there were 176 articles (22%) that underwent full review. Three articles met primary inclusion criteria, with an estimated 8% (95% Confidence Interval (CI) 0.01, 0.14) rate of survival to hospital discharge from a pooled sample of 561 cerebrovascular patients after in-hospital CPR. Twenty articles met secondary inclusion criteria, listing a cerebrovascular comorbidity, with an estimated rate of survival to hospital discharge of 16% (95% CI 0.14, 0.19). All studies demonstrated wide variability in adherence to Utstein guidelines, and neurological outcomes were detailed in only 6 (26%) studies. Among the few studies reporting survival to hospital discharge after CPR among acute cerebrovascular patients, survival is lower than general inpatient populations. These findings synthesize the limited empirical basis for discussions about resuscitation among stroke patients, and highlight the need for more disease stratified reporting of outcomes after inpatient CPR.

Indexed as

Cardiopulmonary ResuscitationCerebrovascular DisordersHeart ArrestHospitalizationHumansSurvival RateCardiopulmonary resuscitationCerebrovascular diseaseCPRStrokeSurvival

Identifiers

PMID29789199
PMCPMC6062458
OpenAlexW2804076075

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.