Evidence map›Paper›PMID 29788954›Full record

ReviewBMC pulmonary medicine2018

Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis.

Jürgen Schäfer, Matthias Griese, Ravishankar Chandrasekaran, Sanjay H Chotirmall, Dominik Hartl

Abstract readReview
In one paragraph

Review in BMC pulmonary medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Human Respiratory Microbiome: Current Understandings and Future Directions.American journal of respiratory cell and molecular biology · 2023
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Inflammatory Phenotypes of Bronchiectasis.Journal of personalized medicine · 2025
    Review
  9. Observational
  10. Review
  11. Insights on the Pathogenesis ofJournal of clinical medicine · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Neutrophil serine proteases in cystic fibrosis: role in disease pathogenesis and rationale as a therapeutic target.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jürgen SchäferDepartment of Radiology, Division of Pediatric Radiology, University of Tübingen, Tübingen, Germany. Juergen.Schaefer@med.uni-tuebingen.de.
Matthias GrieseChildren's Hospital, University of Munich, Munich, Germany.
Ravishankar ChandrasekaranLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Sanjay H ChotirmallLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Dominik HartlDepartment of Pediatrics I, University of Tübingen, Tübingen, Germany.

Funding

National Medical Research Council NMRC/TA/0048/2016
6 · The paper itself

Abstract

Bronchiectasis is a common feature of severe inherited and acquired pulmonary disease conditions. Among inherited diseases, cystic fibrosis (CF) is the major disorder associated with bronchiectasis, while acquired conditions frequently featuring bronchiectasis include post-infective bronchiectasis and chronic obstructive pulmonary disease (COPD). Mechanistically, bronchiectasis is driven by a complex interplay of inflammation and infection with neutrophilic inflammation playing a predominant role. The clinical characterization and management of bronchiectasis should involve a precise diagnostic workup, tailored therapeutic strategies and pulmonary imaging that has become an essential tool for the diagnosis and follow-up of bronchiectasis. Prospective future studies are required to optimize the diagnostic and therapeutic management of bronchiectasis, particularly in heterogeneous non-CF bronchiectasis populations.

Indexed as

BronchiectasisCystic FibrosisHumansLungMagnetic Resonance ImagingMultidetector Computed TomographyPhenotype

Identifiers

PMID29788954
PMCPMC5964733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.