Evidence map›Paper›PMID 29788473›Full record

ArticleSchizophrenia bulletin2018

Enhancing Psychosis-Spectrum Nosology Through an International Data Sharing Initiative.

Anna R Docherty, Eduardo Fonseca-Pedrero, Martin Debbané, Raymond C K Chan, Richard J Linscott, Katherine G Jonas, David C Cicero, Melissa J Green, Leonard J Simms, Oliver Mason and 35 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Schizophrenia bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors.

Anna R DochertyDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT.
Eduardo Fonseca-PedreroDepartment of Psychiatry, Universidad de La Rioja, Oviedo, Spain.
Martin DebbanéResearch Department of Clinical, Educational, and Health Psychology, University College London, London, UK.
Raymond C K ChanNeuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Richard J LinscottDepartment of Psychology, University of Otago, Dunedin, New Zealand.
Katherine G JonasDepartment of Psychiatry, Stony Brook School of Medicine, Stony Brook, NY.
David C CiceroDepartment of Psychology, University of Hawaii at Manoa, Honolulu, HI.
Melissa J GreenSchool of Psychiatry, University of New South Wales, Sydney, Australia.
Leonard J SimmsDepartment of Psychology, University at Buffalo, The State University of New York, Buffalo, NY.
Oliver MasonDepartment of Psychology, University of Surrey, Guildford, UK.
David WatsonDepartment of Psychology, University of Notre Dame, Notre Dame, IN.
Ulrich EttingerDepartment of Psychology, University of Bonn, Bonn, Germany.
Monika WaszczukDepartment of Psychiatry, Stony Brook School of Medicine, Stony Brook, NY.
Alexander RappDepartment of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.
Phillip GrantDepartment of Psychology, Justus-Liebig-University Giessen, Giessen, Germany.
Roman KotovDepartment of Psychiatry, Stony Brook School of Medicine, Stony Brook, NY.
Colin G DeYoungDepartment of Psychology, University of Minnesota, Minneapolis, MN.
Camilo J RuggeroDepartment of Psychology, University of North Texas, Denton, TX.
Nicolas R EatonDepartment of Psychology, Stony Brook University, Stony Brook, NY.
Robert F KruegerDepartment of Psychology, University of Minnesota, Minneapolis, MN.
Christopher PatrickDepartment of Psychology, Florida State University, Tallahassee, FL.
Christopher HopwoodDepartment of Psychology, University of California-Davis, Davis, CA.
F Anthony O'NeillCentre for Public Health, Institute of Clinical Sciences, Queen's University Belfast, Belfast, UK.
David H ZaldDepartment of Psychology, Vanderbilt University, Nashville, TN.
Christopher C ConwayDepartment of Psychology, College of William & Mary, Williamsburg, VA.
Daniel E AdkinsDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT.
Irwin D WaldmanDepartment of Psychology, Emory University, Atlanta, GA.
Jim van OsDepartment of Psychiatry and Psychology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Patrick F SullivanDepartment of Psychiatry, University of North Carolina-Chapel Hill, Chapel Hill, NC.
John S AndersonDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT.
Andrey A ShabalinDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT.
Scott R SponheimDepartment of Psychology, University of Minnesota, Minneapolis, MN.
Stephan F TaylorDepartment of Psychiatry, University of Michigan, Ann Arbor, MI.
Rachel G GraziopleneDepartment of Psychology, Yale University, New Haven, CT.
Silviu A BacanuVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA.
Tim B BigdeliVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA.
Corinna HaenschelDepartment of Psychology, City University, London, UK.
Dolores MalaspinaDepartment of Psychiatry, Icahn School of Medicine, Mount Sinai, New York, NY.
Diane C GoodingDepartment of Psychology, University of Wisconsin-Madison, Madison, WI.
Kristin NicodemusInstitute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Frauke Schultze-LutterDepartment of Psychiatry and Psychotherapy, Heinrich-Heine University, Dusseldorf, Germany.
Neus Barrantes-VidalDepartment of Clinical Psychology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Christine MohrInstitute of Psychology, University of Lausanne, Lausanne, Switzerland.
William T CarpenterDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, MD.
Alex S CohenDepartment of Psychology, Louisiana State University, Baton Rouge, LA.

Funding

Trajectories of Aging in Psychotic Disorders Over 27 YearsR01MH110434 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KOTOV, ROMAN I · 2016 to 2020
$4.5M
1/7 Psychiatric Genomics Consortium: Finding actionable variationU01MH109528 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SULLIVAN, PATRICK F · 2016 to 2020
$2.5M
Trajectories of recovery from psychosis over two decadesR01MH094398 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KOTOV, ROMAN I · 2011 to 2013
$2.2M
Modeling Dimensionality and Genetic Heterogeneity in SchizophreniaK01MH109765 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI DOCHERTY, ANNA R. · 2016 to 2019
$675k
Quantitative Modeling of Visual Perception Endophenotypes in SchizophreniaI01CX000227 · VA · MINNEAPOLIS VA MEDICAL CENTER · PI SPONHEIM, SCOTT R · 2011 to 2018
–
CSRD VA I01 CX000227NIMH NIH HHS K01 MH109765NIMH NIH HHS R01 MH094398NIMH NIH HHS R01 MH110434NIMH NIH HHS U01 MH109528
6 · The paper itself

Abstract

The latent structure of schizotypy and psychosis-spectrum symptoms remains poorly understood. Furthermore, molecular genetic substrates are poorly defined, largely due to the substantial resources required to collect rich phenotypic data across diverse populations. Sample sizes of phenotypic studies are often insufficient for advanced structural equation modeling approaches. In the last 50 years, efforts in both psychiatry and psychological science have moved toward (1) a dimensional model of psychopathology (eg, the current Hierarchical Taxonomy of Psychopathology [HiTOP] initiative), (2) an integration of methods and measures across traits and units of analysis (eg, the RDoC initiative), and (3) powerful, impactful study designs maximizing sample size to detect subtle genomic variation relating to complex traits (the Psychiatric Genomics Consortium [PGC]). These movements are important to the future study of the psychosis spectrum, and to resolving heterogeneity with respect to instrument and population. The International Consortium of Schizotypy Research is composed of over 40 laboratories in 12 countries, and to date, members have compiled a body of schizotypy- and psychosis-related phenotype data from more than 30000 individuals. It has become apparent that compiling data into a protected, relational database and crowdsourcing analytic and data science expertise will result in significant enhancement of current research on the structure and biological substrates of the psychosis spectrum. The authors present a data-sharing infrastructure similar to that of the PGC, and a resource-sharing infrastructure similar to that of HiTOP. This report details the rationale and benefits of the phenotypic data collective and presents an open invitation for participation.

Indexed as

Datasets as TopicModels, TheoreticalHumansInformation DisseminationIntersectoral CollaborationPsychotic DisordersSchizophreniaSchizotypal Personality Disorder

Identifiers

PMID29788473
PMCPMC6188505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.