Evidence map›Paper›PMID 29788461›Full record

SynthesisRheumatology (Oxford, England)2018

Concomitant fibromyalgia complicating chronic inflammatory arthritis: a systematic review and meta-analysis.

Stephen J Duffield, Natasha Miller, Sizheng Zhao, Nicola J Goodson

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Rheumatology (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03740347 (Chronic Non-inflammatory Pains in Rheumatopediatrics), which is not on this map. Cited by 98 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 3 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03740347 withdrawnnot on this map

Chronic Non-inflammatory Pains in Rheumatopediatrics

TypeobservationalSponsorAssistance Publique - Hôpitaux de ParisRan2018 to 2018Enrolled0ConditionsJuvenile Idiopathic ArthritisArmsQuestionnaires
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 3 syntheses or guidelines pooled it, 150 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Effects ofFrontiers in pharmacology · 2026
    Trial
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Unravelling Fibromyalgia in Psoriatic Arthritis.Rheumatology and therapy · 2026
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Towards an individualised approach to pain management in inflammatory arthritis.Therapeutic advances in musculoskeletal disease · 2026
    Review
  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Stephen J DuffieldDepartment of Musculoskeletal Biology 1, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
Natasha MillerSchool of Medicine, University of Liverpool, Liverpool, UK.
Sizheng ZhaoDepartment of Musculoskeletal Biology 1, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
Nicola J GoodsonDepartment of Musculoskeletal Biology 1, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
University of Liverpool · GB

Funding

Arthritis Research UK 20665Medical Research Council
6 · The paper itself

Abstract

Objectives: This systematic review and meta-analysis will describe the prevalence of concomitant FM in adults with inflammatory arthritis and quantify the impact of FM on DAS. Methods: Cochrane library, MEDLINE, Psychinfo, PubMed, Scopus and Web of Science were searched using key terms and predefined exclusion criteria. As appropriate, proportional and pairwise meta-analysis methods were used to pool results. Results: Forty articles were identified. In RA the prevalence of FM ranged from 4.9 to 52.4% (21% pooled). In axSpA the range was 4.11-25.2% (13% pooled in AS only). In PsA the range was 9.6-27.2% (18% pooled). The presence of concomitant FM was related to higher DAS in patients with RA and AS (DAS28 mean difference 1.24, 95% CI: 1.10, 1.37 in RA; BASDAI mean difference 2.22, 95% CI: 1.86, 2.58 in AS). Concomitant FM was also associated with higher DAS in existing PsA studies. Self-reported, rather than objective, components of DAS appear to be raised in the presence of FM (e.g. tender joint count and Visual Analogue Scale (VAS) pain scores). Conclusion: FM is common in RA, AxSpA and PsA. Comorbid FM appears to amplify DAS and could therefore influence management of these rheumatic conditions.

Indexed as

ArthritisChronic DiseaseComorbidityFibromyalgiaGlobal HealthHumansPrevalence

Identifiers

PMID29788461
PMCPMC6055651
OpenAlexW2804058019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.