ArticleNeurosurgery2019
Epidemiology of Symptomatic Chiari Malformation in Tatarstan: Regional and Ethnic Differences in Prevalence.
Article in Neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Efficacy of neurosurgical intervention in syrinx resolution in patients presenting with Chiari malformation type I and syringomyelia: a systematic review and radiological meta-analysis.Neurosurgical review · 2025Pooled it
- Clinical and MRI morphometric characterization of symptomatic cerebellar tonsillar ectopia.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Chiari I malformation.Nature reviews. Disease primers · 2026Review
- Nuclear and Mitochondrial DNA Variants in Chiari Malformation Type 1: Insights from an East Coast Malaysian Cohort.The Eurasian journal of medicine · 2026Article
- MRI-morphometric characterization of Chiari malformation types 0 and 1 with syringomyelia: implications for diagnosis and pathogenesis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Observational
- A Novel Metric for Assessing Long-Term Outcomes in Adults with Chiari Malformation Type I: Occipitocervical Dura Angulation (ODA)-Applications and Value.Cerebellum (London, England) · 2025Article
- Exploring pathogenesis, prevalence, and genetic associations in Chiari malformation type 1: a contemporary perspective.Asian biomedicine : research, reviews and news · 2024Review
- Evaluation and Treatment of Patients with Small Posterior Cranial Fossa and Chiari Malformation, Types 0 and 1.Advances and technical standards in neurosurgery · 2024Article
- Article
- Research process, recap, and prediction of Chiari malformation based on bicentennial history of nomenclature and terms misuse.Neurosurgical review · 2023Review
- Overview of Spontaneous Intracranial Hypotension and Differential Diagnosis with Chiari I Malformation.Journal of clinical medicine · 2023Review
- Amyotrophic Lateral Sclerosis Mimic Syndrome in a 24-Year-Old Man with Chiari 1 Malformation and Syringomyelia: A Clinical Case.Journal of clinical medicine · 2023Article
- A long-term follow-up study of adults with Chiari malformation type I combined with syringomyelia.Frontiers in neurology · 2023Article
- Recovery of diabetes insipidus after Chiari malformation decompression: A rare manifestation of Chiari malformation.Clinical case reports · 2022Article
- The Small Posterior Cranial Fossa Syndrome and Chiari Malformation Type 0.Journal of clinical medicine · 2022Review
- Diagnostic utility of parasagittal measurements of tonsillar herniation in Chiari I malformation.The neuroradiology journal · 2022Article
- Posterior cranial fossa and cervical spine morphometric abnormalities in symptomatic Chiari type 0 and Chiari type 1 malformation patients with and without syringomyelia.Acta neurochirurgica · 2021Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundEpidemiology can assess the effect of Chiari I malformation (CM1) on the neurological health of a population and evaluate factors influencing CM1 development.
objectiveTo analyze the regional and ethnic differences in the prevalence of CM1.
methodsThe population of the Republic of Tatarstan (RT) in the Russian Federation was evaluated for patients with CM1 symptoms over an 11-yr period. Typical symptoms of CM1 were found in 868 patients. Data from neurological examination and magnetic resonance imaging (MRI) measurement of posterior cranial fossa structures were analyzed.
resultsMRI evidence of CM1, defined as cerebellar tonsils lying at least 5 mm inferior to the foramen magnum, was found in 67% of symptomatic patients. Another 33% of symptomatic patients had 2 to 4 mm of tonsillar ectopia, which we defined as "borderline Chiari malformation type 1 (bCM1)." The period prevalence in the entire RT for symptomatic CM1 was 20:100 000; for bCM1 was 10:100 000; and for CM1 and bCM1 together was 30:100 000. Prevalence of patients with CM1 symptoms was greater in the northern than southern districts of Tatarstan, due to a high prevalence (413:100 000) of CM1 in the Baltasy region in one of the northern districts.
conclusionOne-third of patients with typical symptoms of CM1 had less than 5 mm of tonsillar ectopia (bCM1). Assessments of the health impact of CM1-type symptoms on a patient population should include the bCM1 patient group. A regional disease cluster of patients with Chiari malformation was found in Baltasy district of RT and needs further study.
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