Evidence map›Paper›PMID 29788377›Full record

ArticleNucleic acids research2018

WEGO 2.0: a web tool for analyzing and plotting GO annotations, 2018 update.

Jia Ye, Yong Zhang, Huihai Cui, Jiawei Liu, Yuqing Wu, Yun Cheng, Huixing Xu, Xingxin Huang, Shengting Li, An Zhou and 7 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 288 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
288citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

288 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Genome-Wide Identification of thePlants (Basel, Switzerland) · 2026
    Article
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  20. Review

228 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jia YeBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Yong ZhangBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Huihai CuiBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Jiawei LiuBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Yuqing WuBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Yun ChengZhejiang Hospital, Hangzhou, Zhejiang, 310013, China.
Huixing XuBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Xingxin HuangBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Shengting LiBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
An ZhouBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Xiuqing ZhangBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Lars BolundLars Bolund Institute of Regenerative Medicine, BGI-Qingdao, Qingdao, Shandong, 266555, China.
Qiang ChenDepartment of Oncology, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.
Jian WangBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Huanming YangBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Lin FangBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Chunmei ShiDepartment of Oncology, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

WEGO (Web Gene Ontology Annotation Plot), created in 2006, is a simple but useful tool for visualizing, comparing and plotting GO (Gene Ontology) annotation results. Owing largely to the rapid development of high-throughput sequencing and the increasing acceptance of GO, WEGO has benefitted from outstanding performance regarding the number of users and citations in recent years, which motivated us to update to version 2.0. WEGO uses the GO annotation results as input. Based on GO's standardized DAG (Directed Acyclic Graph) structured vocabulary system, the number of genes corresponding to each GO ID is calculated and shown in a graphical format. WEGO 2.0 updates have targeted four aspects, aiming to provide a more efficient and up-to-date approach for comparative genomic analyses. First, the number of input files, previously limited to three, is now unlimited, allowing WEGO to analyze multiple datasets. Also added in this version are the reference datasets of nine model species that can be adopted as baselines in genomic comparative analyses. Furthermore, in the analyzing processes each Chi-square test is carried out for multiple datasets instead of every two samples. At last, WEGO 2.0 provides an additional output graph along with the traditional WEGO histogram, displaying the sorted P-values of GO terms and indicating their significant differences. At the same time, WEGO 2.0 features an entirely new user interface. WEGO is available for free at http://wego.genomics.org.cn.

Indexed as

Gene OntologyInternetSoftwareDatabases, GeneticHigh-Throughput Nucleotide SequencingMolecular Sequence AnnotationUser-Computer Interface

Identifiers

PMID29788377
PMCPMC6030983

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.