ArticleMolecular biology and evolution2018
The Evolution of Gene Expression Underlying Vision Loss in Cave Animals.
Article in Molecular biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 46 citations in OpenAlex.
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- Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticity.eLife · 2025Article
- Reduced adult stem cell fate specification led to eye reduction in cave planarians.Nature communications · 2025Article
- Host and venom evolution in parasitoid wasps: does independently adapting to the same host shape the evolution of the venom gland transcriptome?BMC biology · 2024Article
- Parthenogenetic Stick Insects Exhibit Signatures of Preservation in the Molecular Architecture of Male Reproduction.Genome biology and evolution · 2024Article
- Comparative transcriptomic evidence of physiological changes and potential relationships in vertebrates under different dormancy states.Zoological research · 2024Article
- Evaluating the Performance of Widely Used Phylogenetic Models for Gene Expression Evolution.Genome biology and evolution · 2023Article
- Transcriptome analysis and identification of genes related to environmental adaptation ofEcology and evolution · 2023Article
- Evaluating the Performance of Widely Used Phylogenetic Models for Gene Expression Evolution.bioRxiv : the preprint server for biology · 2023Article
- Mitochondrial phylogeography and molecular evolution of the rhodopsin visual pigment in troglobitic populations ofZoological research · 2023Article
- Genetic assimilation of ancestral plasticity during parallel adaptation to zinc contamination in Silene uniflora.Nature ecology & evolution · 2023Article
- A Phylogenetic Framework to Simulate Synthetic Interspecies RNA-Seq Data.Molecular biology and evolution · 2023Article
- Evolutionary jumps in bacterial GC content.G3 (Bethesda, Md.) · 2022Article
- Different Genes are Recruited During Convergent Evolution of Pregnancy and the Placenta.Molecular biology and evolution · 2022Article
- HawaiianZooKeys · 2021Article
- Genomic Analysis of the Only Blind Cichlid Reveals Extensive Inactivation in Eye and Pigment Formation Genes.Genome biology and evolution · 2020Article
- Article
- Drift and Directional Selection Are the Evolutionary Forces Driving Gene Expression Divergence in Eye and Brain Tissue ofGenetics · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dissecting the evolutionary genetic processes underlying eye reduction and vision loss in obligate cave-dwelling organisms has been a long-standing challenge in evolutionary biology. Independent vision loss events in related subterranean organisms can provide critical insight into these processes as well as into the nature of convergent loss of complex traits. Advances in evolutionary developmental biology have illuminated the significant role of heritable gene expression variation in the evolution of new forms. Here, we analyze gene expression variation in adult eye tissue across the freshwater crayfish, representing four independent vision-loss events in caves. Species and individual expression patterns cluster by eye function rather than phylogeny, suggesting convergence in transcriptome evolution in independently blind animals. However, this clustering is not greater than what is observed in surface species with conserved eye function after accounting for phylogenetic expectations. Modeling expression evolution suggests that there is a common increase in evolutionary rates in the blind lineages, consistent with a relaxation of selective constraint maintaining optimal expression levels. This is evidence for a repeated loss of expression constraint in the transcriptomes of blind animals and that convergence occurs via a similar trajectory through genetic drift.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.