ArticleGenome biology and evolution2018
Comparative Genomics Reveals Thousands of Novel Chemosensory Genes and Massive Changes in Chemoreceptor Repertories across Chelicerates.
Article in Genome biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 49 citations in OpenAlex.
- Article
- Identification and Expression Profiling of Scorpion Ionotropic Receptors and Gustatory Receptors Based on the Transcriptomic Analysis.Integrative zoology · 2026Article
- Transition From Land to Sea: Comparative Genomics Illuminates the Adaptive Evolution of the Intertidal Spider.Molecular ecology resources · 2026Article
- Lineage-specific expansion and positive selection of NPC2 genes in the crab spider Ebrechtella tricuspidata and other arachnids.BMC genomics · 2026Article
- Evolutionary Genomics of Gene Families: A Case Study of Insect Gustatory Receptors.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Chemosensory function of Varroa gnathosoma: transcriptomic and proteomic analyses.Experimental & applied acarology · 2024Article
- Lampshade web spider Ectatosticta davidi chromosome-level genome assembly provides evidence for its phylogenetic position.Communications biology · 2023Article
- Development of a knowledge graph framework to ease and empower translational approaches in plant research: a use-case on grain legumes.Frontiers in artificial intelligence · 2023Article
- Article
- De novo transcriptome sequencing of the northern fowl mite, Ornithonyssus sylviarum, shed light on parasitiform poultry mites evolution and its chemoreceptor repertoires.Parasitology research · 2022Article
- The Tetragnatha kauaiensis Genome Sheds Light on the Origins of Genomic Novelty in Spiders.Genome biology and evolution · 2021Article
- The Odorant-Binding Proteins of the Spider MiteInternational journal of molecular sciences · 2021Article
- A new non-classical fold of varroa odorant-binding proteins reveals a wide open internal cavity.Scientific reports · 2021Article
- Lipocalins in Arthropod Chemical Communication.Genome biology and evolution · 2021Article
- Transcriptomic analysis of the poultry red mite, Dermanyssus gallinae, across all stages of the lifecycle.BMC genomics · 2021Article
- Comparative morphological and transcriptomic analyses reveal chemosensory genes in the poultry red mite, Dermanyssus gallinae.Scientific reports · 2020Article
- The genome sequence of the grape phylloxera provides insights into the evolution, adaptation, and invasion routes of an iconic pest.BMC biology · 2020Article
- Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings.Nature communications · 2020Article
- Comparative Genomics Identifies Putative Signatures of Sociality in Spiders.Genome biology and evolution · 2020Article
- Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemoreception is a widespread biological function that is essential for the survival, reproduction, and social communication of animals. Though the molecular mechanisms underlying chemoreception are relatively well known in insects, they are poorly studied in the other major arthropod lineages. Current availability of a number of chelicerate genomes constitutes a great opportunity to better characterize gene families involved in this important function in a lineage that emerged and colonized land independently of insects. At the same time, that offers new opportunities and challenges for the study of this interesting animal branch in many translational research areas. Here, we have performed a comprehensive comparative genomics study that explicitly considers the high fragmentation of available draft genomes and that for the first time included complete genome data that cover most of the chelicerate diversity. Our exhaustive searches exposed thousands of previously uncharacterized chemosensory sequences, most of them encoding members of the gustatory and ionotropic receptor families. The phylogenetic and gene turnover analyses of these sequences indicated that the whole-genome duplication events proposed for this subphylum would not explain the differences in the number of chemoreceptors observed across species. A constant and prolonged gene birth and death process, altered by episodic bursts of gene duplication yielding lineage-specific expansions, has contributed significantly to the extant chemosensory diversity in this group of animals. This study also provides valuable insights into the origin and functional diversification of other relevant chemosensory gene families different from receptors, such as odorant-binding proteins and other related molecules.
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