Evidence map›Paper›PMID 29788196›Full record

ArticleAmerican journal of hypertension2018

Maternal Weight, Snoring, and Hypertension: Potential Pathways of Associations.

Galit Levi Dunietz, Kerby Shedden, Lynda D Lisabeth, Marjorie C Treadwell, Louise M O'Brien

Abstract read
In one paragraph

Article in American journal of hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Burden of sleep disturbance in non-Hispanic Black pregnant women.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  5. The Berlin Questionnaire in pregnancy predominantly identifies obesity.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Galit Levi DunietzSleep Disorders Center, Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Kerby SheddenDepartment of Statistics, University of Michigan, Ann Arbor, Michigan, USA.
Lynda D LisabethDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Marjorie C TreadwellDepartment of Obstetrics & Gynecology, University of Michigan, Ann Arbor, Michigan, USA.
Louise M O'BrienSleep Disorders Center, Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
TRAINING IN CLINICAL AND BASIC NEUROSCIENCET32NS007222 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Henry L Paulson · 1985 to 2026
$8.0M
Use of PAP in women with pre-eclampsiaK23HL095739 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'BRIEN, LOUISE M. · 2009 to 2013
$604k
The Impact of Sleep-Disordered Breathing on Adverse Pregnancy OutcomesR21HL089918 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'BRIEN, LOUISE M. · 2009 to 2010
$425k
Sleep and Neurobehavioral Performance After Cleft Palate RepairR21HL087819 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'BRIEN, LOUISE M. · 2009 to 2010
$417k
Sleep Disturbances and Adverse Pregnancy Outcomes; Epidemiologic Modeling of Feasible PathwaysF32HD091938 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DUNIETZ, GALIT LEVI · 2017 to 2017
$57k
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NHLBI NIH HHS K23 HL095739NHLBI NIH HHS R21 HL087819NHLBI NIH HHS R21 HL089918NICHD NIH HHS F32 HD091938NINDS NIH HHS T32 NS007222
6 · The paper itself

Abstract

backgroundHypertensive disorders of pregnancy (HDP) are linked to excessive maternal weight and frequent snoring. However, pathways between maternal excessive weight, pregnancy-onset snoring, and HDP are only partially estimated. We examined and quantified the total and direct associations between excessive maternal weight and incident HDP and their indirect pathway through pregnancy-onset snoring.

methodsThird trimester pregnant women enrolled from prenatal clinics of a large tertiary medical center. Sleep data were collected through a questionnaire. Demographic and pregnancy information and first trimester maternal weight were abstracted from medical charts. After exclusion of women with prepregnancy hypertension and/or chronic snoring, causal mediation analysis was used to estimate the total and direct association between maternal weight and incident HDP and their indirect association through pregnancy-onset snoring. The proportion of the mediated association through pregnancy-onset snoring from the total association of maternal weight and HDP was also quantified.

resultsAfter excluding those with chronic hypertension and/or snoring, the final sample included 1,333 pregnant women. In adjusted analysis, excessive maternal weight was directly associated with incident HDP; odds ratio (OR) = 1.87 (95% confidence interval (CI) 1.30, 2.70). Pregnancy-onset snoring significantly mediated the association between maternal weight and incident HDP; OR = 1.08 (95% CI 1.01, 1.17). The mediated pathway accounted for 15% of the total association between maternal weight and incident HDP.

conclusionsPregnancy-onset snoring mediates the association between maternal weight and incident HDP in women without prepregnancy snoring or hypertension. These findings demonstrate the relative contributions of excessive maternal weight and pregnancy-onset snoring to incident HDP.

Indexed as

Blood PressureGestational Weight GainAdultFemaleHumansHypertension, Pregnancy-InducedIncidenceMichiganPregnancyRisk AssessmentRisk FactorsSnoringYoung Adult

Identifiers

PMID29788196
PMCPMC6132116

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.