Evidence map›Paper›PMID 29788053›Full record

ArticleInflammatory bowel diseases2018

Reversing Ongoing Chronic Intestinal Inflammation and Fibrosis by Sustained Block of IL-12 and IL-23 Using a Vaccine in Mice.

Qingdong Guan, Carolyn R Weiss, Shuhe Wang, Gefei Qing, Xi Yang, Richard J Warrington, Charles N Bernstein, Zhikang Peng

Open access · bronzeAbstract read
In one paragraph

Article in Inflammatory bowel diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Oral delivery of recombinantDrug delivery · 2026
    Article
  2. Article
  3. Review
  4. Prospective therapeutics for intestinal and hepatic fibrosis.Bioengineering & translational medicine · 2023
    Review
  5. Review
  6. Vaccination therapy for inflammatory bowel disease.Human vaccines & immunotherapeutics · 2023
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Revisiting fibrosis in inflammatory bowel disease: the gut thickens.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Qingdong GuanDepartment of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
Carolyn R WeissDepartment of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
Shuhe WangDepartment of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.
Gefei QingDepartment of Pathology, University of Manitoba, Winnipeg, Manitoba, Canada.
Xi YangDepartment of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
Richard J WarringtonDepartment of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
Charles N BernsteinDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Zhikang PengDepartment of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
University of Manitoba · CAGansu Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsChronic DiseaseColitisDextran SulfateDisease Models, AnimalFemaleFibrosisInterleukin-12 Subunit p40Interleukin-23IntestinesMiceMice, Inbred BALB CTrinitrobenzenesulfonic AcidVaccines, SubunitDextran SulfateInterleukin-12 Subunit p40Interleukin-23Trinitrobenzenesulfonic AcidVaccines, Subunitand DSS-induced colitisIL-12/IL-23p40 vaccineimmunotherapyTNBS-induced colitis

Identifiers

PMID29788053
PMCPMC6205364
OpenAlexW2803974737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.