ArticleGenome biology and evolution2018
Fast Evolution and Lineage-Specific Gene Family Expansions of Aphid Salivary Effectors Driven by Interactions with Host-Plants.
Article in Genome biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 80 citations in OpenAlex.
- Article
- Gene expression of pea aphid (Hemiptera: Aphididae) salivary effectors changes based on feeding duration and plant species.Journal of insect science (Online) · 2026Article
- Molecular and Structural Characterization of Foam Proteins from Mahanarva spectabilis (Distant, 1909) (Hemiptera: Cercopidae) Nymphs Reveals Adaptive Features and Potential Targets for Pest Control.Archives of insect biochemistry and physiology · 2026Article
- Chromosome scale genomes of two invasive Adelges species enable virtual screening for selective adelgicides.G3 (Bethesda, Md.) · 2026Article
- The Genetics of Host Plant Acceptance in Pea Aphids.Molecular ecology · 2025Article
- Chromosome scale genomes of two invasive Adelges species enable virtual screening for selective adelgicides.bioRxiv : the preprint server for biology · 2025Article
- Host plant flooding stress in soybeans differentially impacts avirulent and virulent soybean aphid (Aphis glycines) biotypes.Scientific reports · 2025Article
- Identification and functional analysis of putative effector proteins fromFrontiers in plant science · 2025Article
- Multi-omics approaches define novel aphid effector candidates associated with virulence and avirulence phenotypes.BMC genomics · 2024Article
- Selection and Gene Duplication Associated With High-Elevation Diversification in Pristimantis, the Largest Terrestrial Vertebrate Genus.Genome biology and evolution · 2024Article
- Article
- A pipeline contributes to efficient identification of salivary proteins in short-headed planthopper, Epeurysa nawaii.Scientific reports · 2024Article
- LC‒MS/MS and transcriptome analyses reveal saliva components of the seed-feeding truebug Pyrrhocoris apterus.Crop health · 2023Article
- Advances in genome sequencing reveal changes in gene content that contribute to arthropod macroevolution.Development genes and evolution · 2023Review
- A Method for Identification of Biotype-Specific Salivary Effector Candidates of Aphid.Insects · 2023Article
- Role of Acrostyle Cuticular Proteins in the Retention of an Aphid Salivary Effector.International journal of molecular sciences · 2022Article
- Virulence strategies of an insect herbivore and oomycete plant pathogen converge on host E3 SUMO ligase SIZ1.The New phytologist · 2022Article
- Article
- A major-effect genetic locus, ApRVII, controlling resistance against both adapted and non-adapted aphid biotypes in pea.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Effector-mediated plant-virus-vector interactions.The Plant cell · 2022Review
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Authors and funding
14 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effector proteins play crucial roles in plant-parasite interactions by suppressing plant defenses and hijacking plant physiological responses to facilitate parasite invasion and propagation. Although effector proteins have been characterized in many microbial plant pathogens, their nature and role in adaptation to host plants are largely unknown in insect herbivores. Aphids rely on salivary effector proteins injected into the host plants to promote phloem sap uptake. Therefore, gaining insight into the repertoire and evolution of aphid effectors is key to unveiling the mechanisms responsible for aphid virulence and host plant specialization. With this aim in mind, we assembled catalogues of putative effectors in the legume specialist aphid, Acyrthosiphon pisum, using transcriptomics and proteomics approaches. We identified 3,603 candidate effector genes predicted to be expressed in A. pisum salivary glands (SGs), and 740 of which displayed up-regulated expression in SGs in comparison to the alimentary tract. A search for orthologs in 17 arthropod genomes revealed that SG-up-regulated effector candidates of A. pisum are enriched in aphid-specific genes and tend to evolve faster compared with the whole gene set. We also found that a large fraction of proteins detected in the A. pisum saliva belonged to three gene families, of which certain members show evidence consistent with positive selection. Overall, this comprehensive analysis suggests that the large repertoire of effector candidates in A. pisum constitutes a source of novelties promoting plant adaptation to legumes.
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