Evidence map›Paper›PMID 29787900›Full record

ArticleEnvironment international2018

Associations between prenatal and childhood PBDE exposure and early adolescent visual, verbal and working memory.

Whitney J Cowell, Amy Margolis, Virginia A Rauh, Andreas Sjödin, Richard Jones, Ya Wang, Wanda Garcia, Frederica Perera, Shuang Wang, Julie B Herbstman

Open access · greenAbstract read
In one paragraph

Article in Environment international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. The Role of Environmental Chemicals in the Etiology of Learning Difficulties: A Novel Theoretical Framework.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2023
    Article
  7. Article
  8. Toxic Effects and Mechanisms of Polybrominated Diphenyl Ethers.International journal of molecular sciences · 2023
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Whitney J CowellColumbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Amy MargolisColumbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Department of Child and Adolescent Psychiatry, Columbia University, New York, NY 10032, USA.
Virginia A RauhColumbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Heilbrunn Department of Population and Family Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Andreas SjödinDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Richard JonesDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Ya WangColumbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Wanda GarciaColumbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Heilbrunn Department of Population and Family Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Frederica PereraColumbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Shuang WangColumbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Julie B HerbstmanColumbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA. Electronic address: jh2678@cumc.columbia.edu.
Center for Children · USCenters for Disease Control and Prevention · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
Assess the Effects of ETS on NeurodevelopmentR01DA027100 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RAUH, VIRGINIA A · 2010 to 2014
$3.3M
Pre- and Postnatal PBDE Exposure, Thyroid Hormones, and NeurodevelopmentR01ES021806 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HERBSTMAN, JULIE BETH · 2012 to 2016
$2.6M
Training Program in Environmental Life Course EpidemiologyT32ES023772 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FACTOR-LITVAK, PAM R, PERERA, FREDERICA P · 2015 to 2019
$1.3M
Prenatal Exposure to Environmental Tobacco Smoke, COVID-19- Related Psychosocial Stress, and Neurodevelopment.K23ES026239 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARGOLIS, AMY · 2016 to 2021
$767k
NIDA NIH HHS R01 DA027100NIEHS NIH HHS K23 ES026239NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES021806NIEHS NIH HHS T32 ES007322NIEHS NIH HHS T32 ES023772
6 · The paper itself

Abstract

backgroundPrenatal and childhood exposure to polybrominated diphenyl ether (PBDE) flame retardants has been inversely associated with cognitive performance, however, few studies have measured PBDE concentrations in samples collected during both prenatal and postnatal periods.

methodsWe examined prenatal (cord) and childhood (ages 2, 3, 5, 7 and 9 years) plasma PBDE concentrations in relation to memory outcomes assessed between the ages of 9 and 14 years. The study sample includes a subset (n = 212) of the African American and Dominican children enrolled in the Columbia Center for Children's Environmental Health Mothers and Newborns birth cohort. We used multivariable linear regression to examine associations between continuous log

resultsAssociations between prenatal exposure and working memory significantly varied by sex (p-interaction = 0.02), with inverse relations observed only among girls (i.e. β

conclusionsExposure to PBDEs during both prenatal and postnatal periods may disrupt memory domains in early adolescence. These findings contribute to a substantial body of evidence supporting the developmental neurotoxicity of PBDEs and underscore the need to reduce exposure among pregnant women and children.

Indexed as

Maternal ExposureAdolescentChildChild, PreschoolEnvironmental ExposureFemaleFetal BloodHalogenated Diphenyl EthersHumansInfant, NewbornMaleMemoryPregnancyTask Performance and AnalysisHalogenated Diphenyl EthersChildhoodFlame retardantMemoryPBDEPrenatalTrajectory

Identifiers

PMID29787900
PMCPMC6460908
OpenAlexW2803179488

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.