Evidence map›Paper›PMID 29787706›Full record

ArticleDevelopmental cell2018

Circuit Wiring: Neurite Speed Dating versus Stable Synaptic Matchmaking.

Heike Blockus, Franck Polleux

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Heike BlockusDepartment of Neuroscience, Columbia University Medical Center, New York, NY 10027, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY, USA.
Franck PolleuxDepartment of Neuroscience, Columbia University Medical Center, New York, NY 10027, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY, USA; Kavli Institute for Brain Sciences, Columbia University Medical Center, New York, NY 10027, USA. Electronic address: fp2304@columbia.edu.
Allen Institute for Brain Science · USColumbia University Irving Medical Center · US

Funding

Slit-Robo signaling links synapse specificity with functional circuit wiringR21NS109753 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI POLLEUX, FRANCK · 2019 to 2019
$446k
NINDS NIH HHS R21 NS109753
6 · The paper itself

Abstract

Understanding the mechanisms establishing the complex but precise pattern of connectivity characterizing neural circuits remains an immense challenge. In a recent issue of Neuron, Mao and colleagues (2018) provide new insights by showing that the activation kinetics of EphB2, a transmembrane receptor tyrosine kinase, control whether dendritic filopodia makes a synapse with candidate axons.

Indexed as

NeuritesSynapsesAxonsDendritesNeurons

Identifiers

PMID29787706
PMCPMC8655511
OpenAlexW2804755383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.