Evidence map›Paper›PMID 29786768›Full record

ArticleAIDS and behavior2018

Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China.

Lu Yin, Yuejuan Zhao, Meridith Blevins Peratikos, Liang Song, Xiangjun Zhang, Ruolei Xin, Zheya Sun, Yunan Xu, Li Zhang, Yifei Hu and 5 more

Abstract readValidation Study
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  8. Prediction Model for the Risk of HIV Infection among MSM in China: Validation and Stability.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Lu YinMedical Research & Biometrics Center, National Center for Cardiovascular Diseases, Beijing, China.
Yuejuan ZhaoBeijing Municipal Center for Disease Control and Prevention & Centers for Preventive Medical Research, Beijing, China.
Meridith Blevins PeratikosDepartments of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Liang SongChaoyang District Center for Disease Control and Prevention, Beijing, China.
Xiangjun ZhangXicheng District Center for Disease Control and Prevention, Beijing, China.
Ruolei XinBeijing Municipal Center for Disease Control and Prevention & Centers for Preventive Medical Research, Beijing, China.
Zheya SunState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, China.
Yunan XuState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, China.
Li ZhangBeijing Municipal Center for Disease Control and Prevention & Centers for Preventive Medical Research, Beijing, China.
Yifei HuState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, China.
Chun HaoSchool of Public Health, Sun Yat-sen University, Guangzhou, China.
Yuhua RuanState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, China.
Yiming ShaoState Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, China.
Sten H VermundVanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, TN, USA. sten.vermund@yale.edu.
Han-Zhu QianVanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, TN, USA.
Beijing Center for Disease Prevention and Control · CNChinese Center For Disease Control and Prevention · CNVanderbilt University Medical Center · USYale University · USCapital Medical University · CNSun Yat-sen University · CNUniversity of Florida · US

Funding

Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5M
Multi-component HIV Intervention Packages for Chinese MSMR01AI094562 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI QIAN, HAN-ZHU, VERMUND, STEN H. · 2011 to 2014
$2.5M
Expanded Testing, Linkage, and Treatment for HIV Prevention Among MSM in ChinaR34AI091446 · NIAID · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2011 to 2011
$226k
FUNCTION OF AND SIGNALING BY THE B CELL PROTEINF32AI009462 · NIAID · STANFORD UNIVERSITY · PI PAN, CHIN · 1996 to 1996
–
National Institute of Allergy and Infectious Diseases P30AI110527National Institute of Allergy and Infectious Diseases R01AI09462National Institute of Allergy and Infectious Diseases R34AI091446NIAID NIH HHS F32 AI009462NIAID NIH HHS P30 AI110527NIAID NIH HHS R01 AI094562NIAID NIH HHS R34 AI091446NIMH NIH HHS P30 MH062294
6 · The paper itself

Abstract

Receptive anal intercourse, multiple partners, condomless sex, sexually transmitted infections (STIs), and drug/alcohol addiction are familiar factors that correlate with increased human immunodeficiency virus (HIV) risk among men who have sex with men (MSM). To improve estimation to HIV acquisition, we created a composite score using questions from routine survey of 3588 MSM in Beijing, China. The HIV prevalence was 13.4%. A risk scoring tool using penalized maximum likelihood multivariable logistic regression modeling was developed, deploying backward step-down variable selection to obtain a reduced-form model. The full penalized model included 19 sexual predictors, while the reduced-form model had 12 predictors. Both models calibrated well; bootstrap-corrected c-indices were 0.70 (full model) and 0.71 (reduced-form model). Non-Beijing residence, short-term living in Beijing, illegal drug use, multiple male sexual partners, receptive anal sex, inconsistent condom use, alcohol consumption before sex, and syphilis infection were the strongest predictors of HIV infection. Discriminating higher-risk MSM for targeted HIV prevention programming using a validated risk score could improve the efficiency of resource deployment for educational and risk reduction programs. A valid risk score can also identify higher risk persons into prevention and vaccine clinical trials, which would improve trial cost-efficiency.

Indexed as

AdolescentAdultAgedAlcohol DrinkingChinaCondomsCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceRisk AssessmentChinaHIVHIV preventionMen who have sex with men (MSM)Risk score

Identifiers

PMID29786768
PMCPMC7024582
OpenAlexW2804545137

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.