Evidence map›Paper›PMID 29786649›Full record

ArticleInternational journal of molecular sciences2018

Kudzu Leaf Extract Suppresses the Production of Inducible Nitric Oxide Synthase, Cyclooxygenase-2, Tumor Necrosis Factor-Alpha, and Interleukin-6 via Inhibition of JNK, TBK1 and STAT1 in Inflammatory Macrophages.

Seok Hyun Eom, So-Jung Jin, Hee-Yeong Jeong, Youngju Song, You Jin Lim, Jong-In Kim, Youn-Hyung Lee, Hee Kang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Differential Influence ofPharmaceuticals (Basel, Switzerland) · 2021
    Article
  8. Bioflavonoid Robinin fromNutrients · 2021
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Seok Hyun EomDepartment of Horticultural Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea. se43@khu.ac.kr.
So-Jung JinDepartment of Horticultural Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea. truesojung@gmail.com.
Hee-Yeong JeongGraduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea. jhy9592@naver.com.
Youngju SongDepartment of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul 02447, Korea. songyj@khu.ac.kr.
You Jin LimDepartment of Horticultural Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea. yujn0213@naver.com.
Jong-In KimDivision of Acupuncture and Moxibustion Medicine, Kyung Hee Korean Medicine Hospital, Kyung Hee University, Seoul 02447, Korea. hann8400@hanmail.net.
Youn-Hyung LeeDepartment of Horticultural Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea. younlee@khu.ac.kr.
Hee KangGraduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea. shehee@khu.ac.kr.ORCID 0000-0001-5576-9317
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kudzu (

Indexed as

AnimalsCells, CulturedCyclooxygenase 2Enzyme InhibitorsInterleukin-6MacrophagesMaleMAP Kinase Kinase 4MiceMice, Inbred BALB CNitric Oxide Synthase Type IIPlant ExtractsPlant LeavesProtein Serine-Threonine KinasesPuerariaSTAT1 Transcription FactorCyclooxygenase 2Enzyme InhibitorsInterleukin-6MAP Kinase Kinase 4Nitric Oxide Synthase Type IIPlant ExtractsProtein Serine-Threonine KinasesStat1 protein, mouseSTAT1 Transcription FactorTbk1 protein, mouseTumor Necrosis Factor-alphainducible nitric oxide synthaseinflammationkudzu leafmacrophagesrobininSTAT1

Identifiers

PMID29786649
PMCPMC5983698
OpenAlexW2804943524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.