Evidence map›Paper›PMID 29786564›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2018

Developing defined substrates for stem cell culture and differentiation.

Louise Hagbard, Katherine Cameron, Paul August, Christopher Penton, Malin Parmar, David C Hay, Therése Kallur

Abstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. In vitro liver models for toxicological research.Drug metabolism and pharmacokinetics · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Long-termAdipocyte · 2022
    Article
  12. Article
  13. Review
  14. Everything You Always Wanted to Know About Organoid-Based Models (and Never Dared to Ask).Cellular and molecular gastroenterology and hepatology · 2022
    Review
  15. Towards organoid culture without Matrigel.Communications biology · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Louise HagbardBioLamina, Löfströms Allé 5A, 172 66 Sundbyberg, Sweden.
Katherine CameronMedical Research Council Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh EH16 4UU, UK.
Paul AugustIcagen, Discovery Biology, Tucson Innovation Center, Oro Valley, AZ 85755, USA.
Christopher PentonIcagen, Discovery Biology, Tucson Innovation Center, Oro Valley, AZ 85755, USA.
Malin ParmarWallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden.
David C HayMedical Research Council Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh EH16 4UU, UK.ORCID 0000-0002-7593-5973
Therése KallurBioLamina, Löfströms Allé 5A, 172 66 Sundbyberg, Sweden therese.kallur@biolamina.com.ORCID 0000-0002-0824-5307

Funding

Medical Research Council MR/K017047/1Medical Research Council MR/K026666/1Medical Research Council MR/L022974/1
6 · The paper itself

Abstract

Over the past few decades, a variety of different reagents for stem cell maintenance and differentiation have been commercialized. These reagents share a common goal in facilitating the manufacture of products suitable for cell therapy while reducing the amount of non-defined components. Lessons from developmental biology have identified signalling molecules that can guide the differentiation process

Indexed as

Cell Culture TechniquesCell DifferentiationExtracellular MatrixHumansLamininStem CellsLaminincell culturecell therapydefined substrateshuman pluripotent stem cellshuman recombinant laminins

Identifiers

PMID29786564
PMCPMC5974452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.