ArticleMolecular plant pathology2018
Evidence for horizontal gene transfer and separation of effector recognition from effector function revealed by analysis of effector genes shared between cape gooseberry- and tomato-infecting formae speciales of Fusarium oxysporum.
Article in Molecular plant pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 71 citations in OpenAlex.
- Genetic and Pathogenic Differentiation ofJournal of fungi (Basel, Switzerland) · 2026Article
- Soil and Foliar Applications of Silicon Mitigate Biotic Stress in Cape Gooseberry Plants Caused by Fusarium Vascular Wilt.Biology · 2026Article
- "Secreted in Xylem" Genes (SIX Genes): Relationship to the Aggressiveness ofPlants (Basel, Switzerland) · 2025Article
- Genomic Differences Between TwoJournal of fungi (Basel, Switzerland) · 2025Article
- Characterization, Genome Sequencing, and Development of a Rapid PCR Identification Primer forPlants (Basel, Switzerland) · 2024Article
- Comparative genomics and transcriptomics reveal differences in effector complement and expression between races ofFrontiers in plant science · 2024Article
- Studying the microbiome of suppressive soils against vascular wilt, caused by Fusarium oxysporum in cape gooseberry (Physalis peruviana).Environmental microbiology reports · 2023Article
- Article
- Functional Genomics and Comparative Lineage-Specific Region Analyses Reveal Novel Insights into Race Divergence in Verticillium dahliae.Microbiology spectrum · 2021Article
- Pro-domain processing of fungal effector proteins from plant pathogens.PLoS pathogens · 2021Article
- Mixtures of Biological Control Agents and Organic Additives Improve Physiological Behavior in Cape Gooseberry Plants under Vascular Wilt Disease.Plants (Basel, Switzerland) · 2021Article
- Physiological Response of Cape Gooseberry Plants toFrontiers in plant science · 2021Article
- Secreted in Xylem Genes: Drivers of Host Adaptation inFrontiers in plant science · 2021Review
- Combining transcriptome analysis and GWAS for identification and validation of marker genes in thePeerJ · 2021Article
- Article
- Bioactive compounds induced in Physalis angulata L. by methyl-jasmonate: an investigation of compound accumulation patterns and biosynthesis-related candidate genes.Plant molecular biology · 2020Article
- Physiological Responses to the Foliar Application of Synthetic Resistance Elicitors in Cape Gooseberry Seedlings Infected withPlants (Basel, Switzerland) · 2020Article
- Characterization of Pathogenic and NonpathogenicPathogens (Basel, Switzerland) · 2020Article
- Screening of DifferentFrontiers in plant science · 2020Article
- Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RNA sequencing (RNAseq) reads from cape gooseberry plants (Physalis peruviana) infected with Fusarium oxysporumf. sp. physali (Foph) were mapped against the lineage-specific transcriptome of Fusarium oxysporumf. sp. lycopersici (Fol) to look for putative effector genes. Homologues of Fol SIX1(designated SIX1a and SIX1b), SIX7, SIX10, SIX12, SIX15 and Ave1were identified. The near identity of the Foph and Fol SIX7, SIX10 and SIX12genes and their intergenic regions suggest that this gene cluster may have undergone recent lateral transfer. Foph SIX1a and SIX1bwere tested for their ability to complement a SIX1 knockout mutant of Fol. This mutant shows reduced pathogenicity on susceptible tomato plants, but is able to infect otherwise resistant tomato plants carrying the I-3 gene for Fusarium wilt resistance (SIX1 corresponds to Avr3). Neither SIX1a nor SIX1b could restore full pathogenicity on susceptible tomato plants, suggesting that any role they may play in pathogenicity is likely to be specific to cape gooseberry. SIX1b, but not SIX1a, was able to restore avirulence on tomato plants carrying I-3.These findings separate the recognition of SIX1 from its role as an effector and suggest direct recognition by I-3. A hypervariable region of SIX1undergoing diversifying selection within the F. oxysporum species complex is likely to play an important role in SIX1 recognition. These findings also indicate that I-3could potentially be deployed as a transgene in cape gooseberry to protect this emerging crop from Foph.Alternatively, cape gooseberry germplasm could be explored for I-3homologues capable of providing resistance to Foph.
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