ArticleIndian journal of ophthalmology2018
Comparison of optical coherence tomography angiography and fundus fluorescein angiography features of retinal capillary hemangioblastoma.
Article in Indian journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 40 citations in OpenAlex.
- Intravitreous treatment of severe ocular von Hippel-Lindau disease using a combination of the VEGF inhibitor, ranibizumab and PDGF inhibitor, E10030: Results from a phase 1/2 clinical trial.Clinical & experimental ophthalmology · 2021Trial
- Retinal Capillary Haemangioblastoma: Clinical Spectrum, Imaging Insights, and Treatment Strategies.Ocular oncology and pathology · 2025Review
- Mathematical modeling and simulation of tumor-induced angiogenesis in retinal hemangioblastoma.PLoS computational biology · 2025Article
- Outcome of optic disc capillary hemangioma following intravitreal ranibizumab injection: A case report.The Journal of international medical research · 2025Article
- Vision-Threatening Complications of Juxtapapillary Retinal Capillary Hemangioma: A Case of Retinal Artery Occlusion.The American journal of case reports · 2025Article
- Hamartomas of the Retina and Optic Disc.Turkish journal of ophthalmology · 2022Article
- 3-D OCT angiographic evidence of Anti-VEGF therapeutic effects on retinal capillary hemangioma.American journal of ophthalmology case reports · 2022Article
- Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device.Frontiers in medicine · 2022Article
- Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions.The ocular surface · 2021Article
- Retinal hemangioblastoma vascular detail elucidated on swept source optical coherence tomography angiography.American journal of ophthalmology case reports · 2021Article
- Structural and microvascular changes of the peripapillary retinal nerve fiber layer in Von Hippel-Lindau disease: an OCT and OCT angiography study.Scientific reports · 2021Article
- Optical Coherence Tomography Angiography of Early Stage 1a Retinal Hemangioblastoma in Von-Hippel-Lindau.Journal of kidney cancer and VHL · 2021Article
- Laser speckle flowgraphy in juxtapapillary retinal capillary hemangioblastoma: a case report on natural course and therapeutic effect.Oncotarget · 2020Article
- Macular Perfusion Impairment in Von Hippel-Lindau Disease Suggests a Generalized Retinal Vessel Alteration.Journal of clinical medicine · 2020Article
- Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas.Translational vision science & technology · 2020Article
- Detection of retinal microvascular changes in von Hippel-Lindau disease using optical coherence tomography angiography.PloS one · 2020Article
- Optical coherence tomography angiography in assessment of response to therapy in retinal capillary hemangioblastoma and diffuse choroidal hemangioma.Indian journal of ophthalmology · 2019Article
- Commentary: Comparison of optical coherence tomography angiography and fundus fluorescein angiography features of retinal capillary hemangioblastoma.Indian journal of ophthalmology · 2018Article
- Optic disc and peripapillary tumors.Taiwan journal of ophthalmologyReview
- Exudative Type 3 Retinal Arteriovenous Malformation in a Pediatric Patient.Case reports in ophthalmologyArticle
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5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study is to compare the optical coherence tomography angiography (OCTA) and fundus fluorescein angiography (FFA) features of retinal capillary hemangioblastoma (RCH). This is an observational case series of three patients with von Hippel-Lindau (VHL) disease and one patient with juxtapapillary RCH. All patients underwent FFA with a mydriatic fundus camera and OCTA with swept-source angio OCT. The FFA and OCTA characteristics of tumors were compared. In our series, FFA could identify tumors as small as the width of a third-order retinal artery, which was missed on clinical examination. OCTA identified these tiny tumors, but only those closer to the posterior pole. Both FFA and OCTA could identify the intrinsic vasculature and feeder vessel in juxtapapillary RCH. On OCTA, the tumors were better defined than in FFA. The depth of the lesion can be identified on OCTA. Feeder and the draining vessels could be identified precisely in OCTA than FFA, particularly in small tumors. OCTA can identify tumors in VHL missed on clinical examination. It can identify the feeder vessel and intrinsic vasculature of sessile juxtapapillary RCH and aids in its diagnosis. Tumors are better defined in OCTA than FFA due to the absence of leakage. However, FFA can identify nearly all the early tumors, but OCTA fails to image the peripheral tumors due to its smaller field and prolonged acquisition time. Technological advances and the development of wide-field OCTA in the future can be helpful in identifying all the unsuspected tumors in VHL disease.
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