Evidence map›Paper›PMID 29785681›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2018

Diabetes symptoms predictors of health-related quality of life in adolescents and young adults with type 1 or type 2 diabetes.

James W Varni, Alan M Delamater, Korey K Hood, Jennifer K Raymond, Kimberly A Driscoll, Jenise C Wong, Saleh Adi, Joyce P Yi-Frazier, Ellen K Grishman, Melissa A Faith and 8 more

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

18 authors.

James W VarniDepartment of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, 3137 TAMU, College Station, TX, 77843-3137, USA. jvarni@arch.tamu.edu.
Alan M DelamaterDepartment of Pediatrics, Mailman Center for Child Development, University of Miami Miller School of Medicine, Miami, FL, USA.
Korey K HoodDivision of Pediatric Endocrinology and Diabetes, Stanford University School of Medicine, Stanford, CA, USA.
Jennifer K RaymondCenter for Endocrinology, Diabetes, & Metabolism, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Kimberly A DriscollDepartment of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Denver, Denver, CO, USA.
Jenise C WongThe Madison Clinic for Pediatric Diabetes and Department of Pediatrics, Division of Endocrinology, University of California San Francisco, San Francisco, CA, USA.
Saleh AdiThe Madison Clinic for Pediatric Diabetes and Department of Pediatrics, Division of Endocrinology, University of California San Francisco, San Francisco, CA, USA.
Joyce P Yi-FrazierSeattle Children's Research Institute, Seattle, WA, USA.
Ellen K GrishmanDivision of Pediatric Endocrinology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Melissa A FaithDivision of Pediatric Endocrinology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Sarah D CorathersDepartment of Pediatrics, Division of Endocrinology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Jessica C KichlerDivision of Behavioral Medicine and Clinical Psychology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Jennifer L MillerDivision of Pediatric Endocrinology, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Elena M DoskeyDepartment of Educational Psychology, Texas A&M University, College Station, TX, USA.
Vincent P AguirreDepartment of Psychology, Texas A&M University, College Station, TX, USA.
Robert W HefferDepartment of Psychology, Texas A&M University, College Station, TX, USA.
Don P WilsonCook Children's Medical Center, Fort Worth, TX, USA.
Pediatric Quality of Life Inventory™ 3.2 Diabetes Module Testing Study Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective was to investigate the patient-reported diabetes symptoms predictors of generic health-related quality of life (HRQOL) in adolescents and young adults (AYA) with type 1 or type 2 diabetes.

methodsThe 15-item PedsQL™ 3.2 Diabetes Module Diabetes Symptoms Summary Score and PedsQL™ 4.0 Generic Core Scales were completed in a 10-site national field test study by 513 AYA ages 13-25 years with type 1 (n = 424) or type 2 (n = 89) diabetes. Diabetes symptoms were tested for bivariate and multivariate linear associations with generic HRQOL.

resultsDiabetes symptoms were associated with decreased HRQOL in bivariate analyses. In predictive analytics models utilizing hierarchical multiple regression analyses controlling for relevant demographic and clinical covariates, diabetes symptoms accounted for 38 and 39% of the variance in patient-reported generic HRQOL for type 1 and type 2 diabetes, respectively, reflecting large effect sizes. The diabetes symptoms facets hyperglycemia symptoms, hypoglycemia symptoms, and nonspecific diabetes symptoms individually accounted for a significant percentage of the variance in separate exploratory predictive analytics models after controlling for demographic and clinical covariates, with small-to-large effect sizes.

conclusionsDiabetes symptoms are potentially modifiable predictors of generic HRQOL in AYA with diabetes. Identifying specific diabetes symptoms or symptoms facets that are the most important predictors from the patient perspective facilitates a patient-centered approach in clinical research, clinical trials, and practice designed to enhance overall generic HRQOL in AYA with diabetes.

Indexed as

AdolescentAdultDiabetes Mellitus, Type 2FemaleHumansMaleQuality of LifeSurveys and QuestionnairesYoung AdultDiabetesHealth-related quality of lifePatient-reported outcomesPediatricsPedsQLSymptomsType 1 diabetesType 2 diabetes

Identifiers

PMID29785681

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.