Evidence map›Paper›PMID 29785661›Full record

ReviewInternational urology and nephrology2018

Atrial fibrillation in dialysis patients: is there a place for non-vitamin K antagonist oral anticoagulants?

Elzbieta Mlodawska, Paulina Lopatowska, Jolanta Malyszko, Maciej Banach, Bożena Sobkowicz, Adrian Covic, Anna Tomaszuk-Kazberuk

Abstract readReview
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In one paragraph

Review in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Elzbieta MlodawskaDepartment of Cardiology, Medical University in Bialystok, Białystok, Poland.
Paulina LopatowskaDepartment of Cardiology, Medical University in Bialystok, Białystok, Poland.ORCID http://orcid.org/0000-0002-4104-4339
Jolanta MalyszkoDepartment of Nephrology, Dialysis and Internal Medicine, Warsaw Medical University, Warsaw, Poland.
Maciej BanachDepartment of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Lodz, Poland.
Bożena SobkowiczDepartment of Cardiology, Medical University in Bialystok, Białystok, Poland.
Adrian CovicNephrology Clinic, Dialysis and Renal Transplant Center - 'C.I. Parhon' University Hospital, and 'Grigore T. Popa' University of Medicine, Iasi, Romania.
Anna Tomaszuk-KazberukDepartment of Cardiology, Medical University in Bialystok, Białystok, Poland. a.tomaszuk@poczta.pl.
Medical University of Białystok · PLGrigore T. Popa University of Medicine and Pharmacy · ROMedical University of Lodz · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) occurs approximately in 3% of general population, with greater prevalence in elderly. Non-vitamin K-dependent oral anticoagulant agents (NOACs) according to the current European guidelines are recommended for patients with AF at high risk for stroke as a first-choice treatment. NOACs are not inferior to warfarin or some of them are better than warfarin in reducing the rate of ischemic stroke. Moreover, they significantly reduce the rate of intracranial hemorrhages, major bleedings, and mortality compared with warfarin. Nevertheless according to ESC guidelines, NOACs are not recommended in patients with creatinine clearance < 30 mL/min. Observational studies provide contradictive data. Only few new trials are ongoing. Therefore, it is not clear if NOACs should be in the future prescribed to patients with advanced CKD and those on dialysis. Moreover, the risk of stroke and bleeding is much higher in such population than in patients without end-stage renal disease (ESRD). The authors provide data on pros and cons of use of NOACs in ESRD patients with AF.

Indexed as

Renal DialysisAnticoagulantsAtrial FibrillationBrain IschemiaDabigatranHumansPractice Guidelines as TopicPyrazolesPyridinesPyridonesRenal Insufficiency, ChronicRivaroxabanStrokeThiazolesAnticoagulantsapixabanDabigatranedoxabanPyrazolesPyridinesPyridonesRivaroxabanThiazolesAtrial fibrillationDialysisNon-vitamin K antagonist oral anticoagulants

Identifiers

PMID29785661
OpenAlexW2804805300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.