SynthesisEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2018
A systematic review and meta-analysis of the use of resuscitative endovascular balloon occlusion of the aorta in the management of major exsanguination.
Synthesis in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 157 citations in OpenAlex.
- Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention from the European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Guideline
- Resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major trauma and uncontrolled haemorrhagic shock: a systematic review with meta-analysis.World journal of emergency surgery : WJES · 2021Pooled it
- The UK resuscitative endovascular balloon occlusion of the aorta in trauma patients with life-threatening torso haemorrhage: the (UK-REBOA) multicentre RCT.Health technology assessment (Winchester, England) · 2024Trial
- Clinical Learning-Curve Evidence and Experience-Related Temporal Trends of Resuscitative Endovascular Balloon Occlusion of the Aorta in Patients with Trauma: A Systematic Review.Journal of clinical medicine · 2026Review
- Hemostatic Resuscitation in Trauma-Induced Coagulopathy: A Comprehensive Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Hydrogen Molecule Delivery System to Ischemic Intestine Using Resuscitative Endovascular Balloon Occlusion of Aorta in Hemorrhagic Shock-A Proof-of-Concept Study.Biomedicines · 2026Article
- Temporary hemodynamic response with resuscitative endovascular balloon occlusion of the aorta (REBOA) during cardiopulmonary resuscitation in a case of traumatic cardiac arrest.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- A Case of Hemorrhagic Shock for a Ruptured Splenic Aneurysm Treated With REBOA-Assisted Surgery.Case reports in surgery · 2025Article
- Safety or speed? Assessing alternative vascular access for angiography after resuscitative endovascular balloon occlusion of the aorta (REBOA) in severe pelvic trauma patients.Trauma surgery & acute care open · 2025Article
- [Focus emergency medicine 2023/2024-Summary of selected studies in emergency medicine].Die Anaesthesiologie · 2024Review
- Using Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) as a Rescue Strategy in Severe Postpartum Hemorrhage: A Case Report.Diagnostics (Basel, Switzerland) · 2024Article
- Resuscitative Endovascular Balloon Occlusion of The Aorta (REBOA) And Mortality in Hemorrhagic Shock Associated with Severe Pelvic Fracture: a National Data Analysis.BMC emergency medicine · 2024Article
- The novel use of resuscitative endovascular balloon occlusion of the aorta for uncontrolled bleeding in a surgically inaccessible abdomen: The ruptured proper hepatic artery in a frozen abdomen.Trauma case reports · 2024Article
- Resuscitative endovascular balloon occlusion of the aorta in out-of-hospital cardiac arrest - A Delphi consensus study for uniform data collection.Resuscitation plus · 2023Article
- The Management of Ruptured Abdominal Aortic Aneurysms: An Ongoing Challenge.Journal of clinical medicine · 2023Review
- Quality monitoring of resuscitative endovascular balloon occlusion of the aorta using cumulative sum analysis in Korea: a case series.Journal of trauma and injury · 2023Article
- The role of REBOA in patients in traumatic cardiac arrest subsequent to hemorrhagic shock: a scoping review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Article
- Needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major haemorrhage: a cross-sectional study.Emergency medicine journal : EMJ · 2022Article
- Article
- Resuscitative endovascular balloon occlusion of the aorta: the postpartum haemorrhage perspective.Critical care (London, England) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCirculatory collapse is a leading cause of mortality among traumatic major exsanguination and in ruptured aortic aneurysm patients. Approximately 40% of patients die before hemorrhage control is achieved. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an adjunct designed to sustain the circulation until definitive surgical or endovascular repair. A systematic review was conducted for the current clinical use of REBOA in patients with hemodynamic instability and to discuss its potential role in improving prehospital and in-hospital outcome.
methodsSystematic review and meta-analysis (1900-2017) using MEDLINE, Cochrane, EMBASE, Web of Science and Central and Emcare using the keywords "aortic balloon occlusion", "aortic balloon tamponade", "REBOA", and "Resuscitative Endovascular Balloon Occlusion" in combination with hemorrhage control, hemorrhage, resuscitation, shock, ruptured abdominal or thoracic aorta, endovascular repair, and open repair. Original published studies on human subjects were considered.
resultsA total of 490 studies were identified; 89 met criteria for inclusion. Of the 1436 patients, overall reported mortality was 49.2% (613/1246) with significant differences (p < 0.001) between clinical indications. Hemodynamic shock was evident in 79.3%, values between clinical indications showed significant difference (p < 0.001). REBOA was favored as treatment in trauma patients in terms of mortality. Pooled analysis demonstrated an increase in mean systolic pressure by almost 50 mmHg following REBOA use.
conclusionREBOA has been used in trauma patients and ruptured aortic aneurysm patients with improvement of hemodynamic parameters and outcomes for several decades. Formal, prospective study is warranted to clarify the role of this adjunct in all hemodynamic unstable patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.