Evidence map›Paper›PMID 29785564›Full record

ReviewPaediatric drugs2018

Helicobacter pylori Infection in Pediatric Patients: Update on Diagnosis and Eradication Strategies.

Kallirroi Kotilea, Nicolas Kalach, Matjaž Homan, Patrick Bontems

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Paediatric drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Significance and Related Factors ofPediatric gastroenterology, hepatology & nutrition · 2025
    Article
  4. Clinical Dilemmas for the Diagnosis and Treatment ofPediatric gastroenterology, hepatology & nutrition · 2024
    Review
  5. ACG case reports journal · 2024
    Article
  6. Antibiotics (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Usefulness of Molecular Methods forInternational journal of molecular sciences · 2022
    Article
  9. Article
  10. Article
  11. Increased Antibiotic Resistance in Children withPathogens (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Kallirroi KotileaDepartment of Pediatric Gastroenterology, Université Libre de Bruxelles, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium.
Nicolas KalachDepartment of Paediatrics, Saint Antoine Paediatric Hospital, Saint Vincent de Paul Hospital, Groupement des Hôpitaux de l'Institut Catholique de Lille (GHICL), Catholic University of Lille, Lille, France.
Matjaž HomanDepartment of Gastroenterology, Hepatology and Nutrition, University of Ljubljana, University Children's Hospital, Ljubljana, Slovenia.
Patrick BontemsDepartment of Pediatric Gastroenterology, Université Libre de Bruxelles, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium. patrick.bontems@huderf.be.ORCID http://orcid.org/0000-0002-5185-5071
Université Libre de Bruxelles · BEUniversité de Lille · FRUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori infection is acquired mainly in childhood and remains an essential cause of peptic ulcer disease and gastric cancer. This article provides commentary on the last ESPGHAN/NASPGHAN guidelines and on publications made after the consensus conference of 2015. The majority of infected children are asymptomatic and pediatric studies do not support a role for H. pylori in functional disorders such as recurrent abdominal pain. The role of H. pylori infection in failure to thrive, children's growth, type I diabetes mellitus (T1DM), and celiac disease remains controversial. The diagnosis of infection should be based on upper-digestive endoscopy with biopsy-based methods. Eradication control after treatment should be based on validated non-invasive tests. Nodular gastritis is the main endoscopic finding of childhood H. pylori infection, but gastroduodenal erosions/ulcers are seen in some children, especially after 10 years of age. When indicated, eradication treatment should be given when good compliance is expected and based on the antimicrobial susceptibility profile.

Indexed as

Helicobacter pyloriAnti-Bacterial AgentsChildDrug Therapy, CombinationHelicobacter InfectionsHumansPractice Guidelines as TopicProton Pump InhibitorsAnti-Bacterial AgentsProton Pump Inhibitors

Identifiers

PMID29785564
OpenAlexW2803705301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.