ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2019
Parkinson's disease increases the risk of perioperative complications after total knee arthroplasty: a nationwide database study.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Management of Osteoporosis in Parkinson's Disease: A Systematic Review of Clinical Practice Guidelines.Movement disorders clinical practice · 2025Pooled it
- Mind the Gap: Predictors of Osteoporosis Treatment Following Fragility Fracture in Parkinsonism.Movement disorders clinical practice · 2026Article
- Parkinson's Disease Patients Face Higher 90-Day Readmission, Reoperation, and Infection Risk Following Total Knee Arthroplasty.Arthroplasty today · 2026Article
- Unicompartmental knee arthroplasty in patients with Parkinson's disease.Archives of orthopaedic and trauma surgery · 2026Article
- Survival of total knee arthroplasty in patients with Parkinson's disease: a registry study.International orthopaedics · 2025Article
- A Low Life's Simple 7 Score Is an Independent Risk Factor for Postoperative Delirium After Total Knee Arthroplasty.Medicina (Kaunas, Lithuania) · 2025Article
- Assessing and managing bone health and fracture risk in Parkinson's disease: the BONE PARK 2 protocol.Age and ageing · 2025Article
- Treatment of Postoperative Instability Following Total Knee Arthroplasty in Patients With Parkinson's Disease.Arthroplasty today · 2024Review
- The effect of Parkinson's disease on total knee arthroplasty: a systematic review and meta-analysis.Knee surgery & related research · 2023Article
- The impact of Parkinson's disease on results of primary total knee arthroplasty.EFORT open reviews · 2022Review
- Association of sleep disturbance with Parkinson disease: evidence from the Women's Health Initiative.Menopause (New York, N.Y.) · 2022Observational
- Urinary Tract Infection in Parkinson's Disease.Journal of Parkinson's disease · 2022Review
- Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson's disease: a multi-institutional retrospective cohort study.BMC musculoskeletal disorders · 2021Article
- Functional outcomes after total joint arthroplasty are related to the severity of Parkinson's disease: a mid-term follow-up.Journal of orthopaedic surgery and research · 2019Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTherefore, the purpose of this study was to evaluate the short-term perioperative outcomes of PD patients who underwent total knee arthroplasty (TKA). We specifically evaluated: (1) perioperative surgical and medical complications; (2) lengths of stay (LOS); and (3) total hospital charges.
methodsThe Nationwide Inpatient Sample was used to identify PD patients who underwent TKA between 2002 and 2013. To control for potential confounders, PD TKA and non-PD TKA patients were propensity score matched (1:3) based on age, sex, ethnicity, Charlson Comorbidity Index, and insurance type. A total of 31,979 PD and 95,596 non-PD TKA patients were included.
resultsPD patients had a 44% higher risk of suffering from any complication (OR 1.44; 95% CI 1.35-1.54), a 45% increased risk for any medical complication (OR 1.45; 95% CI 1.36-1.55), and a 9% higher risk for any surgical complication (OR 1.09; 95% CI 0.84-1.41). Compared to the matched cohort, PD patients had a mean LOS that was 6.5% longer (95% CI 5.46-7.54) and mean total hospital charges that were 3.05% higher (95% CI 1.99-4.11).
conclusionsPD patients are more likely to have postoperative complications, longer LOS, and higher costs after TKA than non-PD TKA patients. Since many of these complications can be prevented, a team-based multi-specialty patient optimization is needed. LEVEL OF EVIDENCE: Level III, therapeutic study.
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