Evidence map›Paper›PMID 29785422›Full record

ArticleChemical communications (Cambridge, England)2018

Super-resolution force spectroscopy reveals ribosomal motion at sub-nucleotide steps.

Haina Jia, Yuhong Wang, Shoujun Xu

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Haina JiaDepartment of Chemistry, University of Houston, Houston, TX 77204, USA. sxu7@uh.edu.
Yuhong Wang
Shoujun Xu
University of Houston · US

Funding

EF-Tu mutagenesis and functional studyR01GM111452 · NIGMS · UNIVERSITY OF HOUSTON · PI YUHONG WANG, Shoujun Xu · 2015 to 2026
$3.2M
NIGMS NIH HHS R01 GM111452
6 · The paper itself

Abstract

Probing biomolecular motion beyond a single nucleotide is technically challenging but fundamentally significant. We have developed super-resolution force spectroscopy (SURFS) with 0.5 pN force resolution and revealed that the ribosome moves by half a nucleotide upon the formation of the pre-translocation complex, which is beyond the resolution of other techniques.

Indexed as

MotionDNA ProbesNucleotidesOligodeoxyribonucleotidesProtein ConformationPuromycinRibosomesRNA, MessengerSpectinomycinSpectrum AnalysisUltrasonic WavesDNA ProbesNucleotidesOligodeoxyribonucleotidesPuromycinRNA, MessengerSpectinomycin

Identifiers

PMID29785422
PMCPMC5989005
OpenAlexW2802853019

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.